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Vitrification of Mouse MII Oocyte Decreases the Mitochondrial DNA Copy Number, TFAM Gene Expression and Mitochondrial Enzyme Activity

BACKGROUND: The objective of this study was determination of the changes in the reactive oxygen species (ROS) level, mitochondrial DNA (mtDNA) copy number and enzyme activity and transcription factor A (TFAM) gene expression in oocytes after vitrification. METHODS: The oocytes at metaphase II (MII)...

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Detalles Bibliográficos
Autores principales: Amoushahi, Mahboobeh, Salehnia, Mojdeh, Mowla, Seyed Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691250/
https://www.ncbi.nlm.nih.gov/pubmed/29201664