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Transgenic mice with ectopic expression of constitutively active TLR4 in adipose tissues do not show impaired insulin sensitivity
INTRODUCTION: Chronic low‐grade inflammation is associated with obesity and diabetes. However, what causes and mediates chronic inflammation in metabolic disorders is not well understood. Toll‐like receptor 4 (TLR4) mediates both infection‐induced and sterile inflammation by recognizing pathogen‐ass...
Autores principales: | Ono‐Moore, Kikumi D., Zhao, Ling, Huang, Shurong, Kim, Jeonga, Rutkowsky, Jennifer M., Snodgrass, Ryan G., Schneider, Dina A., Quon, Michael J., Graham, James L., Havel, Peter J., Hwang, Daniel H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691308/ https://www.ncbi.nlm.nih.gov/pubmed/28776958 http://dx.doi.org/10.1002/iid3.162 |
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