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Tregitopes and impaired antigen presentation: Drivers of the immunomodulatory effects of IVIg?

INTRODUCTION: Although intravenous immunoglobulin (IVIg) is commonly used in the clinic to treat various autoimmune and severe inflammatory diseases, the mode of action is not fully elucidated. This work investigates two proposed mechanisms: (1) the potential role of regulatory T‐cell epitopes (Treg...

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Detalles Bibliográficos
Autores principales: Sordé, Laetitia, Spindeldreher, Sebastian, Palmer, Ed, Karle, Anette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691310/
https://www.ncbi.nlm.nih.gov/pubmed/28560793
http://dx.doi.org/10.1002/iid3.167