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Chemoselective Intermolecular Cross-Enolate-Type Coupling of Amides
[Image: see text] A new approach for the synthesis of 1,4-dicarbonyl compounds is reported. Chemoselective activation of amide carbonyl functionality and subsequent umpolung viaN-oxide addition generates an electrophilic enolonium species that can be coupled with a wide range of nucleophilic enolate...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691317/ https://www.ncbi.nlm.nih.gov/pubmed/29099184 http://dx.doi.org/10.1021/jacs.7b08813 |