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The Molecular Tweezer CLR01 Stabilizes a Disordered Protein–Protein Interface
[Image: see text] Protein regions that are involved in protein–protein interactions (PPIs) very often display a high degree of intrinsic disorder, which is reduced during the recognition process. A prime example is binding of the rigid 14-3-3 adapter proteins to their numerous partner proteins, whos...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691318/ https://www.ncbi.nlm.nih.gov/pubmed/29039919 http://dx.doi.org/10.1021/jacs.7b07939 |