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Effects of Amprenavir on HIV-1 Maturation, Production and Infectivity Following Drug Withdrawal in Chronically-Infected Monocytes/Macrophages

A paucity of information is available on the activity of protease inhibitors (PI) in chronically-infected monocyte-derived macrophages (MDM) and on the kinetics of viral-rebound after PI removal in vitro. To fill this gap, the activity of different concentrations of amprenavir (AMP) was evaluated in...

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Detalles Bibliográficos
Autores principales: Borrajo, Ana, Ranazzi, Alessandro, Pollicita, Michela, Bruno, Rosalinda, Modesti, Andrea, Alteri, Claudia, Perno, Carlo Federico, Svicher, Valentina, Aquaro, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691629/
https://www.ncbi.nlm.nih.gov/pubmed/28956865
http://dx.doi.org/10.3390/v9100277