Mutation of a Conserved Nuclear Export Sequence in Chikungunya Virus Capsid Protein Disrupts Host Cell Nuclear Import

Transmitted by mosquitoes; chikungunya virus (CHIKV) is responsible for frequent outbreaks of arthritic disease in humans. CHIKV is an arthritogenic alphavirus of the Togaviridae family. Capsid protein, a structural protein encoded by the CHIKV RNA genome, is able to translocate to the host cell nuc...

Descripción completa

Detalles Bibliográficos
Autores principales: Jacobs, Susan C., Taylor, Adam, Herrero, Lara J., Mahalingam, Suresh, Fazakerley, John K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691657/
https://www.ncbi.nlm.nih.gov/pubmed/29053568
http://dx.doi.org/10.3390/v9100306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691657/
https://www.ncbi.nlm.nih.gov/pubmed/29053568
http://dx.doi.org/10.3390/v9100306

Ejemplares similares