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Dietary Anthocyanins against Obesity and Inflammation

Chronic low-grade inflammation plays a pivotal role in the pathogenesis of obesity, due to its associated chronic diseases such as type II diabetes, cardiovascular diseases, pulmonary diseases and cancer. Thus, targeting inflammation is an attractive strategy to counter the burden of obesity-induced...

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Autores principales: Lee, Yoon-Mi, Yoon, Young, Yoon, Haelim, Park, Hyun-Min, Song, Sooji, Yeum, Kyung-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691706/
https://www.ncbi.nlm.nih.gov/pubmed/28974032
http://dx.doi.org/10.3390/nu9101089
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author Lee, Yoon-Mi
Yoon, Young
Yoon, Haelim
Park, Hyun-Min
Song, Sooji
Yeum, Kyung-Jin
author_facet Lee, Yoon-Mi
Yoon, Young
Yoon, Haelim
Park, Hyun-Min
Song, Sooji
Yeum, Kyung-Jin
author_sort Lee, Yoon-Mi
collection PubMed
description Chronic low-grade inflammation plays a pivotal role in the pathogenesis of obesity, due to its associated chronic diseases such as type II diabetes, cardiovascular diseases, pulmonary diseases and cancer. Thus, targeting inflammation is an attractive strategy to counter the burden of obesity-induced health problems. Recently, food-derived bioactive compounds have been spotlighted as a regulator against various chronic diseases due to their low toxicity, as opposed to drugs that induce severe side effects. Here we describe the beneficial effects of dietary anthocyanins on obesity-induced metabolic disorders and inflammation. Red cabbage microgreen, blueberry, blackcurrant, mulberry, cherry, black elderberry, black soybean, chokeberry and jaboticaba peel contain a variety of anthocyanins including cyanidins, delphinidins, malvidins, pelargonidins, peonidins and petunidins, and have been reported to alter both metabolic markers and inflammatory markers in cells, animals, and humans. This review discusses the interplay between inflammation and obesity, and their subsequent regulation via the use of dietary anthocyanins, suggesting an alternative dietary strategy to ameliorate obesity and obesity associated chronic diseases.
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spelling pubmed-56917062017-11-22 Dietary Anthocyanins against Obesity and Inflammation Lee, Yoon-Mi Yoon, Young Yoon, Haelim Park, Hyun-Min Song, Sooji Yeum, Kyung-Jin Nutrients Review Chronic low-grade inflammation plays a pivotal role in the pathogenesis of obesity, due to its associated chronic diseases such as type II diabetes, cardiovascular diseases, pulmonary diseases and cancer. Thus, targeting inflammation is an attractive strategy to counter the burden of obesity-induced health problems. Recently, food-derived bioactive compounds have been spotlighted as a regulator against various chronic diseases due to their low toxicity, as opposed to drugs that induce severe side effects. Here we describe the beneficial effects of dietary anthocyanins on obesity-induced metabolic disorders and inflammation. Red cabbage microgreen, blueberry, blackcurrant, mulberry, cherry, black elderberry, black soybean, chokeberry and jaboticaba peel contain a variety of anthocyanins including cyanidins, delphinidins, malvidins, pelargonidins, peonidins and petunidins, and have been reported to alter both metabolic markers and inflammatory markers in cells, animals, and humans. This review discusses the interplay between inflammation and obesity, and their subsequent regulation via the use of dietary anthocyanins, suggesting an alternative dietary strategy to ameliorate obesity and obesity associated chronic diseases. MDPI 2017-10-01 /pmc/articles/PMC5691706/ /pubmed/28974032 http://dx.doi.org/10.3390/nu9101089 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Lee, Yoon-Mi
Yoon, Young
Yoon, Haelim
Park, Hyun-Min
Song, Sooji
Yeum, Kyung-Jin
Dietary Anthocyanins against Obesity and Inflammation
title Dietary Anthocyanins against Obesity and Inflammation
title_full Dietary Anthocyanins against Obesity and Inflammation
title_fullStr Dietary Anthocyanins against Obesity and Inflammation
title_full_unstemmed Dietary Anthocyanins against Obesity and Inflammation
title_short Dietary Anthocyanins against Obesity and Inflammation
title_sort dietary anthocyanins against obesity and inflammation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691706/
https://www.ncbi.nlm.nih.gov/pubmed/28974032
http://dx.doi.org/10.3390/nu9101089
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