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Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men

The effects of citrulline malate (CM) on muscle recovery from resistance exercise remains unknown. We aimed to determine if citrulline malate supplementation improves muscle recovery after a single session of high-intensity resistance exercise (RE) in untrained young adult men. Nine young adult men...

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Autores principales: da Silva, Douglas K., Jacinto, Jeferson L., de Andrade, Walquiria B., Roveratti, Mirela C., Estoche, José M., Balvedi, Mario C. W., de Oliveira, Douglas B., da Silva, Rubens A., Aguiar, Andreo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691748/
https://www.ncbi.nlm.nih.gov/pubmed/29057836
http://dx.doi.org/10.3390/nu9101132
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author da Silva, Douglas K.
Jacinto, Jeferson L.
de Andrade, Walquiria B.
Roveratti, Mirela C.
Estoche, José M.
Balvedi, Mario C. W.
de Oliveira, Douglas B.
da Silva, Rubens A.
Aguiar, Andreo F.
author_facet da Silva, Douglas K.
Jacinto, Jeferson L.
de Andrade, Walquiria B.
Roveratti, Mirela C.
Estoche, José M.
Balvedi, Mario C. W.
de Oliveira, Douglas B.
da Silva, Rubens A.
Aguiar, Andreo F.
author_sort da Silva, Douglas K.
collection PubMed
description The effects of citrulline malate (CM) on muscle recovery from resistance exercise remains unknown. We aimed to determine if citrulline malate supplementation improves muscle recovery after a single session of high-intensity resistance exercise (RE) in untrained young adult men. Nine young adult men (24.0 ± 3.3 years) participated in a double-blind crossover study in which they received 6 g of CM and placebo (PL) on two occasions, separated by a seven-day washout period. Each occasion consisted of a single session of high-intensity RE (0 h) and three subsequent fatigue tests sessions (at 24, 48, and 72 h) to assess the time course of muscle recovery. During the tests sessions, we assessed the following variables: number of maximum repetitions, electromyographic signal (i.e., root mean square (RMS) and median frequency (MF)), muscle soreness and perceived exertion, as well as blood levels of creatine kinase (CK), lactate, insulin, and testosterone:cortisol ratio. CK levels increased at 24 h post-exercise and remained elevate at 48 and 72 h, with no difference between CM and PL conditions. Muscle soreness increased at 24 h post-exercise, which progressively returned to baseline at 72 h in both conditions. Lactate levels increased immediately post-exercise and remained elevated at 24, 48, and 72 h in both conditions. No significant treatment × time interaction was found for all dependents variables (maximum repetitions, perceived exertion, CK, lactate, RMS, MF, and testosterone:cortisol ratio) during the recovery period. In conclusion, our data indicate that CM supplementation (single 6 g dose pre-workout) does not improve the muscle recovery process following a high-intensity RE session in untrained young adult men.
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spelling pubmed-56917482017-11-22 Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men da Silva, Douglas K. Jacinto, Jeferson L. de Andrade, Walquiria B. Roveratti, Mirela C. Estoche, José M. Balvedi, Mario C. W. de Oliveira, Douglas B. da Silva, Rubens A. Aguiar, Andreo F. Nutrients Article The effects of citrulline malate (CM) on muscle recovery from resistance exercise remains unknown. We aimed to determine if citrulline malate supplementation improves muscle recovery after a single session of high-intensity resistance exercise (RE) in untrained young adult men. Nine young adult men (24.0 ± 3.3 years) participated in a double-blind crossover study in which they received 6 g of CM and placebo (PL) on two occasions, separated by a seven-day washout period. Each occasion consisted of a single session of high-intensity RE (0 h) and three subsequent fatigue tests sessions (at 24, 48, and 72 h) to assess the time course of muscle recovery. During the tests sessions, we assessed the following variables: number of maximum repetitions, electromyographic signal (i.e., root mean square (RMS) and median frequency (MF)), muscle soreness and perceived exertion, as well as blood levels of creatine kinase (CK), lactate, insulin, and testosterone:cortisol ratio. CK levels increased at 24 h post-exercise and remained elevate at 48 and 72 h, with no difference between CM and PL conditions. Muscle soreness increased at 24 h post-exercise, which progressively returned to baseline at 72 h in both conditions. Lactate levels increased immediately post-exercise and remained elevated at 24, 48, and 72 h in both conditions. No significant treatment × time interaction was found for all dependents variables (maximum repetitions, perceived exertion, CK, lactate, RMS, MF, and testosterone:cortisol ratio) during the recovery period. In conclusion, our data indicate that CM supplementation (single 6 g dose pre-workout) does not improve the muscle recovery process following a high-intensity RE session in untrained young adult men. MDPI 2017-10-18 /pmc/articles/PMC5691748/ /pubmed/29057836 http://dx.doi.org/10.3390/nu9101132 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
da Silva, Douglas K.
Jacinto, Jeferson L.
de Andrade, Walquiria B.
Roveratti, Mirela C.
Estoche, José M.
Balvedi, Mario C. W.
de Oliveira, Douglas B.
da Silva, Rubens A.
Aguiar, Andreo F.
Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men
title Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men
title_full Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men
title_fullStr Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men
title_full_unstemmed Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men
title_short Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men
title_sort citrulline malate does not improve muscle recovery after resistance exercise in untrained young adult men
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691748/
https://www.ncbi.nlm.nih.gov/pubmed/29057836
http://dx.doi.org/10.3390/nu9101132
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