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Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men
The effects of citrulline malate (CM) on muscle recovery from resistance exercise remains unknown. We aimed to determine if citrulline malate supplementation improves muscle recovery after a single session of high-intensity resistance exercise (RE) in untrained young adult men. Nine young adult men...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691748/ https://www.ncbi.nlm.nih.gov/pubmed/29057836 http://dx.doi.org/10.3390/nu9101132 |
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author | da Silva, Douglas K. Jacinto, Jeferson L. de Andrade, Walquiria B. Roveratti, Mirela C. Estoche, José M. Balvedi, Mario C. W. de Oliveira, Douglas B. da Silva, Rubens A. Aguiar, Andreo F. |
author_facet | da Silva, Douglas K. Jacinto, Jeferson L. de Andrade, Walquiria B. Roveratti, Mirela C. Estoche, José M. Balvedi, Mario C. W. de Oliveira, Douglas B. da Silva, Rubens A. Aguiar, Andreo F. |
author_sort | da Silva, Douglas K. |
collection | PubMed |
description | The effects of citrulline malate (CM) on muscle recovery from resistance exercise remains unknown. We aimed to determine if citrulline malate supplementation improves muscle recovery after a single session of high-intensity resistance exercise (RE) in untrained young adult men. Nine young adult men (24.0 ± 3.3 years) participated in a double-blind crossover study in which they received 6 g of CM and placebo (PL) on two occasions, separated by a seven-day washout period. Each occasion consisted of a single session of high-intensity RE (0 h) and three subsequent fatigue tests sessions (at 24, 48, and 72 h) to assess the time course of muscle recovery. During the tests sessions, we assessed the following variables: number of maximum repetitions, electromyographic signal (i.e., root mean square (RMS) and median frequency (MF)), muscle soreness and perceived exertion, as well as blood levels of creatine kinase (CK), lactate, insulin, and testosterone:cortisol ratio. CK levels increased at 24 h post-exercise and remained elevate at 48 and 72 h, with no difference between CM and PL conditions. Muscle soreness increased at 24 h post-exercise, which progressively returned to baseline at 72 h in both conditions. Lactate levels increased immediately post-exercise and remained elevated at 24, 48, and 72 h in both conditions. No significant treatment × time interaction was found for all dependents variables (maximum repetitions, perceived exertion, CK, lactate, RMS, MF, and testosterone:cortisol ratio) during the recovery period. In conclusion, our data indicate that CM supplementation (single 6 g dose pre-workout) does not improve the muscle recovery process following a high-intensity RE session in untrained young adult men. |
format | Online Article Text |
id | pubmed-5691748 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-56917482017-11-22 Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men da Silva, Douglas K. Jacinto, Jeferson L. de Andrade, Walquiria B. Roveratti, Mirela C. Estoche, José M. Balvedi, Mario C. W. de Oliveira, Douglas B. da Silva, Rubens A. Aguiar, Andreo F. Nutrients Article The effects of citrulline malate (CM) on muscle recovery from resistance exercise remains unknown. We aimed to determine if citrulline malate supplementation improves muscle recovery after a single session of high-intensity resistance exercise (RE) in untrained young adult men. Nine young adult men (24.0 ± 3.3 years) participated in a double-blind crossover study in which they received 6 g of CM and placebo (PL) on two occasions, separated by a seven-day washout period. Each occasion consisted of a single session of high-intensity RE (0 h) and three subsequent fatigue tests sessions (at 24, 48, and 72 h) to assess the time course of muscle recovery. During the tests sessions, we assessed the following variables: number of maximum repetitions, electromyographic signal (i.e., root mean square (RMS) and median frequency (MF)), muscle soreness and perceived exertion, as well as blood levels of creatine kinase (CK), lactate, insulin, and testosterone:cortisol ratio. CK levels increased at 24 h post-exercise and remained elevate at 48 and 72 h, with no difference between CM and PL conditions. Muscle soreness increased at 24 h post-exercise, which progressively returned to baseline at 72 h in both conditions. Lactate levels increased immediately post-exercise and remained elevated at 24, 48, and 72 h in both conditions. No significant treatment × time interaction was found for all dependents variables (maximum repetitions, perceived exertion, CK, lactate, RMS, MF, and testosterone:cortisol ratio) during the recovery period. In conclusion, our data indicate that CM supplementation (single 6 g dose pre-workout) does not improve the muscle recovery process following a high-intensity RE session in untrained young adult men. MDPI 2017-10-18 /pmc/articles/PMC5691748/ /pubmed/29057836 http://dx.doi.org/10.3390/nu9101132 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article da Silva, Douglas K. Jacinto, Jeferson L. de Andrade, Walquiria B. Roveratti, Mirela C. Estoche, José M. Balvedi, Mario C. W. de Oliveira, Douglas B. da Silva, Rubens A. Aguiar, Andreo F. Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men |
title | Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men |
title_full | Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men |
title_fullStr | Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men |
title_full_unstemmed | Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men |
title_short | Citrulline Malate Does Not Improve Muscle Recovery after Resistance Exercise in Untrained Young Adult Men |
title_sort | citrulline malate does not improve muscle recovery after resistance exercise in untrained young adult men |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691748/ https://www.ncbi.nlm.nih.gov/pubmed/29057836 http://dx.doi.org/10.3390/nu9101132 |
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