Expression and significance of B7-H3 and Tie-2 in the tumor vasculature of clear cell renal carcinoma

Tumor angiogenesis is required for tumor growth and metastasis, and the Ang/Tie-2 axis plays a pivotal role in angiogenesis. B7-H3, a new member of the B7 family of costimulatory molecules, has a critical function in the T-cell-mediated antitumor immune response, and abnormal tumor B7-H3 expression...

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Detalles Bibliográficos
Autores principales: Zhang, Xianyun, Ji, Jindong, Zhang, Guangbo, Fang, Chuntao, Jiang, Fujin, Ma, Song, Hou, Jianquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692197/
https://www.ncbi.nlm.nih.gov/pubmed/29180874
http://dx.doi.org/10.2147/OTT.S147041

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