Cargando…

Synergistic malaria vaccine combinations identified by systematic antigen screening

A highly effective vaccine would be a valuable weapon in the drive toward malaria elimination. No such vaccine currently exists, and only a handful of the hundreds of potential candidates in the parasite genome have been evaluated. In this study, we systematically evaluated 29 antigens likely to be...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bustamante, Leyla Y., Powell, Gareth T., Lin, Yen-Chun, Macklin, Michael D., Cross, Nadia, Kemp, Alison, Cawkill, Paula, Sanderson, Theo, Crosnier, Cecile, Muller-Sienerth, Nicole, Doumbo, Ogobara K., Traore, Boubacar, Crompton, Peter D., Cicuta, Pietro, Tran, Tuan M., Wright, Gavin J., Rayner, Julian C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2017
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692528/ https://www.ncbi.nlm.nih.gov/pubmed/29078270 http://dx.doi.org/10.1073/pnas.1702944114

Ejemplares similares

An in vitro erythrocyte preference assay reveals that Plasmodium falciparum parasites prefer Type O over Type A erythrocytes
por: Theron, Michel, et al.
Publicado: (2018)

Identifying novel Plasmodium falciparum erythrocyte invasion receptors using systematic extracellular protein interaction screens
por: Bartholdson, S Josefin, et al.
Publicado: (2013)

High-throughput screens to identify novel interactions between erythrocyte multi-pass receptors and P. falciparum merozoite surface ligands that are involved in invasion
por: Wanaguru, Madushi, et al.
Publicado: (2010)

Semaphorin-7A Is an Erythrocyte Receptor for P. falciparum Merozoite-Specific TRAP Homolog, MTRAP
por: Bartholdson, S. Josefin, et al.
Publicado: (2012)

Impact of Acute Malaria on Pre-Existing Antibodies to Viral and Vaccine Antigens in Mice and Humans
por: Banga, Simran, et al.
Publicado: (2015)

Therapeutic PD-L1 and LAG-3 blockade rapidly clears established blood-stage Plasmodium infection
por: Butler, Noah S., et al.
Publicado: (2011)

A novel population of memory‐activated natural killer cells associated with low parasitaemia in Plasmodium falciparum‐exposed sickle‐cell trait children
por: Loiseau, Claire, et al.
Publicado: (2020)

A nested real-time PCR assay for the quantification of Plasmodium falciparum DNA extracted from dried blood spots
por: Tran, Tuan M, et al.
Publicado: (2014)

B cell analysis of ethnic groups in Mali with differential susceptibility to malaria
por: Portugal, Silvia, et al.
Publicado: (2012)

Plasmodium falciparum Gametocyte-Specific Antibody Profiling Reveals Boosting through Natural Infection and Identifies Potential Markers of Gametocyte Exposure
por: Skinner, Jeff, et al.
Publicado: (2015)

Stool microbiota composition is associated with the prospective risk of Plasmodium falciparum infection
por: Yooseph, Shibu, et al.
Publicado: (2015)

128 A whole-blood transcriptional signature predicts parasite control and protection from malaria fever during natural Plasmodium falciparum infection
por: Tran, Tuan M., et al.
Publicado: (2014)

Co-infection of Long-Term Carriers of Plasmodium falciparum with Schistosoma haematobium Enhances Protection from Febrile Malaria: A Prospective Cohort Study in Mali
por: Doumbo, Safiatou, et al.
Publicado: (2014)

Genetic Resistance to Malaria Is Associated With Greater Enhancement of Immunoglobulin (Ig)M Than IgG Responses to a Broad Array of Plasmodium falciparum Antigens
por: Arama, Charles, et al.
Publicado: (2015)

A full-length recombinant Plasmodium falciparum PfRH5 protein induces inhibitory antibodies that are effective across common PfRH5 genetic variants
por: Bustamante, Leyla Y., et al.
Publicado: (2013)

Extent and Dynamics of Polymorphism in the Malaria Vaccine Candidate Plasmodium falciparum Reticulocyte–Binding Protein Homologue-5 in Kalifabougou, Mali
por: Ouattara, Amed, et al.
Publicado: (2018)

Malaria-induced interferon-γ drives the expansion of Tbet(hi) atypical memory B cells
por: Obeng-Adjei, Nyamekye, et al.
Publicado: (2017)

A Positive Correlation between Atypical Memory B Cells and Plasmodium falciparum Transmission Intensity in Cross-Sectional Studies in Peru and Mali
por: Weiss, Greta E., et al.
Publicado: (2011)

Gut Microbiota Elicits a Protective Immune Response against Malaria Transmission
por: Yilmaz, Bahtiyar, et al.
Publicado: (2014)

Exposure-Dependent Control of Malaria-Induced Inflammation in Children
por: Portugal, Silvia, et al.
Publicado: (2014)

Urinary schistosomiasis among preschool-aged children in Sahelian rural communities in Mali
por: Dabo, Abdoulaye, et al.
Publicado: (2011)

Factors associated with coverage of praziquantel for schistosomiasis control in the community-direct intervention (CDI) approach in Mali (West Africa)
por: Dabo, Abdoulaye, et al.
Publicado: (2013)

Interethnic Differences in Antigen-Presenting Cell Activation and TLR Responses in Malian Children during Plasmodium falciparum Malaria
por: Arama, Charles, et al.
Publicado: (2011)

A library of functional recombinant Plasmodium falciparum merozoite surface proteins
por: Crosnier, Cecile, et al.
Publicado: (2010)

Biochemical Analysis of the Plasmodium falciparum Erythrocyte-binding Antigen-175 (EBA175)-Glycophorin-A Interaction: IMPLICATIONS FOR VACCINE DESIGN
por: Wanaguru, Madushi, et al.
Publicado: (2013)

BASIGIN is a receptor essential for erythrocyte invasion by Plasmodium falciparum
por: Crosnier, Cécile, et al.
Publicado: (2011)

The Plasmodium falciparum-Specific Human Memory B Cell Compartment Expands Gradually with Repeated Malaria Infections
por: Weiss, Greta E., et al.
Publicado: (2010)

Use of a pLDH-based dipstick in the diagnostic and therapeutic follow-up of malaria patients in Mali
por: Ouattara, Amed, et al.
Publicado: (2011)

Changes in the levels of cytokines, chemokines and malaria-specific antibodies in response to Plasmodium falciparum infection in children living in sympatry in Mali
por: Boström, Stéphanie, et al.
Publicado: (2012)

Malaria-associated atypical memory B cells exhibit markedly reduced B cell receptor signaling and effector function
por: Portugal, Silvia, et al.
Publicado: (2015)

Efficacy of Artesunate + Sulfamethoxypyrazine/Pyrimethamine versus Praziquantel in the Treatment of Schistosoma haematobium in Children
por: Sissoko, Mahamadou S., et al.
Publicado: (2009)

Do advanced glycation end-products play a role in malaria susceptibility?
por: Traoré, Karim, et al.
Publicado: (2016)

Dendritic cell responses to Plasmodium falciparum in a malaria-endemic setting
por: Turner, Triniti C., et al.
Publicado: (2021)

Evidence for exposure dependent carriage of malaria parasites across the dry season: modelling analysis of longitudinal data
por: Stadler, Eva, et al.
Publicado: (2023)

Optimal mode for delivery of seasonal malaria chemoprevention in Ouelessebougou, Mali: A cluster randomized trial
por: Barry, Amadou, et al.
Publicado: (2018)

Biochemical and Functional Analysis of Two Plasmodium falciparum Blood-Stage 6-Cys Proteins: P12 and P41
por: Taechalertpaisarn, Tana, et al.
Publicado: (2012)

Artemisinin-based combinations versus amodiaquine plus sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Faladje, Mali
por: Kayentao, Kassoum, et al.
Publicado: (2009)

Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory phenotype
por: Guha, Rajan, et al.
Publicado: (2021)

Memory CD8(+) T cell compartment associated with delayed onset of Plasmodium falciparum infection and better parasite control in sickle‐cell trait children
por: Loiseau, Claire, et al.
Publicado: (2021)

A rapid and scalable method for selecting recombinant mouse monoclonal antibodies
por: Crosnier, Cécile, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_6jthj8ho78tnlhrfrendrif632