GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency

To elucidate the molecular basis of BMP4-induced differentiation of human pluripotent stem cells (PSCs) toward progeny with trophectoderm characteristics, we produced transcriptome, epigenome H3K4me3, H3K27me3, and CpG methylation maps of trophoblast progenitors, purified using the surface marker AP...

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Detalles Bibliográficos
Autores principales: Krendl, Christian, Shaposhnikov, Dmitry, Rishko, Valentyna, Ori, Chaido, Ziegenhain, Christoph, Sass, Steffen, Simon, Lukas, Müller, Nikola S., Straub, Tobias, Brooks, Kelsey E., Chavez, Shawn L., Enard, Wolfgang, Theis, Fabian J., Drukker, Micha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692555/
https://www.ncbi.nlm.nih.gov/pubmed/29078328
http://dx.doi.org/10.1073/pnas.1708341114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692555/
https://www.ncbi.nlm.nih.gov/pubmed/29078328
http://dx.doi.org/10.1073/pnas.1708341114

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