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Structural basis of human kinesin-8 function and inhibition

Kinesin motors play diverse roles in mitosis and are targets for antimitotic drugs. The clinical significance of these motors emphasizes the importance of understanding the molecular basis of their function. Equally important, investigations into the modes of inhibition of these motors provide cruci...

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Detalles Bibliográficos
Autores principales:	Locke, Julia, Joseph, Agnel Praveen, Peña, Alejandro, Möckel, Martin M., Mayer, Thomas U., Topf, Maya, Moores, Carolyn A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2017
Materias:	PNAS Plus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692573/ https://www.ncbi.nlm.nih.gov/pubmed/29078367 http://dx.doi.org/10.1073/pnas.1712169114

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