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Twenty-five years of mTOR: Uncovering the link from nutrients to growth
In my PNAS Inaugural Article, I describe the development of the mTOR field, starting with efforts to understand the mechanism of action of the drug rapamycin, which ∼25 y ago led to the discovery of the mTOR protein kinase. I focus on insights that we have contributed and on work that has been parti...
Autor principal: | Sabatini, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692607/ https://www.ncbi.nlm.nih.gov/pubmed/29078414 http://dx.doi.org/10.1073/pnas.1716173114 |
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