Mycolactone displays anti-inflammatory effects on the nervous system

BACKGROUND: Mycolactone is a macrolide produced by the skin pathogen Mycobacterium ulcerans, with cytotoxic, analgesic and immunomodulatory properties. The latter were recently shown to result from mycolactone blocking the Sec61-dependent production of pro-inflammatory mediators by immune cells. Her...

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Detalles Bibliográficos
Autores principales: Isaac, Caroline, Mauborgne, Annie, Grimaldi, Alfonso, Ade, Kemy, Pohl, Michel, Limatola, Cristina, Boucher, Yves, Demangel, Caroline, Guenin-Macé, Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693295/
https://www.ncbi.nlm.nih.gov/pubmed/29149212
http://dx.doi.org/10.1371/journal.pntd.0006058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693295/
https://www.ncbi.nlm.nih.gov/pubmed/29149212
http://dx.doi.org/10.1371/journal.pntd.0006058

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