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Mycolactone displays anti-inflammatory effects on the nervous system
BACKGROUND: Mycolactone is a macrolide produced by the skin pathogen Mycobacterium ulcerans, with cytotoxic, analgesic and immunomodulatory properties. The latter were recently shown to result from mycolactone blocking the Sec61-dependent production of pro-inflammatory mediators by immune cells. Her...
Autores principales: | Isaac, Caroline, Mauborgne, Annie, Grimaldi, Alfonso, Ade, Kemy, Pohl, Michel, Limatola, Cristina, Boucher, Yves, Demangel, Caroline, Guenin-Macé, Laure |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693295/ https://www.ncbi.nlm.nih.gov/pubmed/29149212 http://dx.doi.org/10.1371/journal.pntd.0006058 |
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