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L-arginine availability and arginase activity: Characterization of amino acid permease 3 in Leishmania amazonensis
BACKGROUND: Leishmania uses the amino acid L-arginine as a substrate for arginase, enzyme that produces urea and ornithine, last precursor of polyamine pathway. This pathway is used by the parasite to replicate and it is essential to establish the infection in the mammalian host. L-arginine is not s...
Autores principales: | Aoki, Juliana Ide, Muxel, Sandra Marcia, Zampieri, Ricardo Andrade, Acuña, Stephanie Maia, Fernandes, Juliane Cristina Ribeiro, Vanderlinde, Rubia Heloisa, Sales, Maria Carmen Oliveira de Pinho, Floeter-Winter, Lucile Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693463/ https://www.ncbi.nlm.nih.gov/pubmed/29073150 http://dx.doi.org/10.1371/journal.pntd.0006025 |
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