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Peripheral immune tolerance alleviates the intracranial lipopolysaccharide injection-induced neuroinflammation and protects the dopaminergic neurons from neuroinflammation-related neurotoxicity

BACKGROUND: Neuroinflammation plays a critical role in the onset and development of neurodegeneration disorders such as Parkinson’s disease. The immune activities of the central nervous system are profoundly affected by peripheral immune activities. Immune tolerance refers to the unresponsiveness of...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Xie, Xin, Xia, Li-Ping, Lv, Hong, Lou, Fan, Ren, Yan, He, Zhi-Yi, Luo, Xiao-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693474/
https://www.ncbi.nlm.nih.gov/pubmed/29145874
http://dx.doi.org/10.1186/s12974-017-0994-3

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