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Alarmin S100A8 Activates Alveolar Epithelial Cells in the Context of Acute Lung Injury in a TLR4-Dependent Manner

Alveolar epithelial cells (AECs) are an essential part of the respiratory barrier in lungs for gas exchange and protection against pathogens. Damage to AECs occurs during lung injury and PAMPs/DAMPs have been shown to activate AECs. However, their interplay as well as the mechanism of AECs’ activati...

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Detalles Bibliográficos
Autores principales: Chakraborty, Deblina, Zenker, Stefanie, Rossaint, Jan, Hölscher, Anna, Pohlen, Michele, Zarbock, Alexander, Roth, Johannes, Vogl, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693860/
https://www.ncbi.nlm.nih.gov/pubmed/29180999
http://dx.doi.org/10.3389/fimmu.2017.01493