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Induction of Robust B Cell Responses after Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells
Modified mRNA vaccines have developed into an effective and well-tolerated vaccine platform that offers scalable and precise antigen production. Nevertheless, the immunological events leading to strong antibody responses elicited by mRNA vaccines are largely unknown. In this study, we demonstrate th...
Autores principales: | Lindgren, Gustaf, Ols, Sebastian, Liang, Frank, Thompson, Elizabeth A., Lin, Ang, Hellgren, Fredrika, Bahl, Kapil, John, Shinu, Yuzhakov, Olga, Hassett, Kimberly J., Brito, Luis A., Salter, Hugh, Ciaramella, Giuseppe, Loré, Karin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693886/ https://www.ncbi.nlm.nih.gov/pubmed/29181005 http://dx.doi.org/10.3389/fimmu.2017.01539 |
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