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Induction of Robust B Cell Responses after Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells

Modified mRNA vaccines have developed into an effective and well-tolerated vaccine platform that offers scalable and precise antigen production. Nevertheless, the immunological events leading to strong antibody responses elicited by mRNA vaccines are largely unknown. In this study, we demonstrate th...

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Detalles Bibliográficos
Autores principales: Lindgren, Gustaf, Ols, Sebastian, Liang, Frank, Thompson, Elizabeth A., Lin, Ang, Hellgren, Fredrika, Bahl, Kapil, John, Shinu, Yuzhakov, Olga, Hassett, Kimberly J., Brito, Luis A., Salter, Hugh, Ciaramella, Giuseppe, Loré, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693886/
https://www.ncbi.nlm.nih.gov/pubmed/29181005
http://dx.doi.org/10.3389/fimmu.2017.01539

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