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PNPLA3 variant and portal/periportal histological pattern in patients with biopsy-proven non-alcoholic fatty liver disease: a possible role for oxidative stress

Pathogenesis of non-alcoholic fatty liver disease (NAFLD) is influenced by predisposing genetic variations, dysmetabolism, systemic oxidative stress, and local cellular and molecular cross-talks. Patatin-like phospholipase domain containing 3 (PNPLA3) gene I148M variant is a known determinant of NAF...

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Detalles Bibliográficos
Autores principales:	Carpino, Guido, Pastori, Daniele, Baratta, Francesco, Overi, Diletta, Labbadia, Giancarlo, Polimeni, Licia, Di Costanzo, Alessia, Pannitteri, Gaetano, Carnevale, Roberto, Del Ben, Maria, Arca, Marcello, Violi, Francesco, Angelico, Francesco, Gaudio, Eugenio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693899/ https://www.ncbi.nlm.nih.gov/pubmed/29150621 http://dx.doi.org/10.1038/s41598-017-15943-z

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