Cargando…

Primary aldosteronism patients show skin alterations and abnormal activation of glucocorticoid receptor in keratinocytes

Primary aldosteronism (PA) is a disease characterized by high aldosterone levels caused by benign adrenal tumors being the most frequent cause of secondary hypertension. Aldosterone plays vital physiological roles through the mineralocorticoid receptor (MR) but in certain cell types, it can also act...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boix, Julia, Bigas, Judit, Sevilla, Lisa M., Iacobone, Maurizio, Citton, Marilisa, Torresan, Francesca, Caroccia, Brasilina, Rossi, Gian Paolo, Pérez, Paloma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693903/ https://www.ncbi.nlm.nih.gov/pubmed/29150654 http://dx.doi.org/10.1038/s41598-017-16216-5

Ejemplares similares

Effect of unilateral adrenalectomy on the quality of life of patients with lateralized primary aldosteronism
por: Citton, Marilisa, et al.
Publicado: (2019)

Aldosterone and cortisol synthesis regulation by angiotensin-(1-7) and angiotensin-converting enzyme 2 in the human adrenal cortex
por: Caroccia, Brasilina, et al.
Publicado: (2021)

Epidermal glucocorticoid and mineralocorticoid receptors act cooperatively to regulate epidermal development and counteract skin inflammation
por: Bigas, Judit, et al.
Publicado: (2018)

OR06-04 Environmental Pollutants Perfluoroalkyl Acids Potently Stimulated Aldosterone Biosynthesis
por: Caroccia, Brasilina, et al.
Publicado: (2023)

Comparison of Cortisol, Androstenedione and Metanephrines to Assess Selectivity and Lateralization of Adrenal Vein Sampling in Primary Aldosteronism
por: Ceolotto, Giulio, et al.
Publicado: (2021)

Glucocorticoid-dependent transcription in skin requires epidermal expression of the glucocorticoid receptor and is modulated by the mineralocorticoid receptor
por: Sevilla, Lisa M., et al.
Publicado: (2020)

Aldosterone Biosynthesis Is Potently Stimulated by Perfluoroalkyl Acids: A Link between Common Environmental Pollutants and Arterial Hypertension
por: Caroccia, Brasilina, et al.
Publicado: (2023)

FRI126 Autoreactive T Cells To Angiotensin II Type 1 Receptor In Salt-dependent Hypertension Due To Primary Aldosteronism
por: Scarpa, Riccardo, et al.
Publicado: (2023)

Urotensin II Exerts Pressor Effects By Stimulating Renin And Aldosterone Synthase Gene Expression
por: Caroccia, Brasilina, et al.
Publicado: (2017)

The Key Role of Epithelial to Mesenchymal Transition (EMT) in Hypertensive Kidney Disease
por: Seccia, Teresa, et al.
Publicado: (2019)

Letter to editor on “Thirty‐six‐month results of laparoscopic‐based renal denervation plus unilateral laparoscopic adrenalectomy for the treatment of patients with resistant hypertension caused by unilateral aldosterone‐producing Adenoma”
por: Schiavone, Donatella, et al.
Publicado: (2021)

Keratinocyte-Targeted Overexpression of the Glucocorticoid Receptor Delays Cutaneous Wound Healing
por: Sanchis, Ana, et al.
Publicado: (2012)

Clinical Features, Treatment, and Surveillance of Hyperparathyroidism-Jaw Tumor Syndrome: An Up-to-Date and Review of the Literature
por: Torresan, Francesca, et al.
Publicado: (2019)

Total adrenalectomy versus subtotal adrenalectomy for bilateral pheochromocytoma: meta-analysis
por: Schiavone, Donatella, et al.
Publicado: (2023)

Roles of the Glucocorticoid and Mineralocorticoid Receptors in Skin Pathophysiology
por: Sevilla, Lisa M., et al.
Publicado: (2018)

Characteristics and Outcomes in Primary Aldosteronism Patients Harboring Glucocorticoid-Remediable Aldosteronism
por: Cheng, Chung-Yi, et al.
Publicado: (2021)

Glucocorticoids and Glucocorticoid-Induced-Leucine-Zipper (GILZ) in Psoriasis
por: Sevilla, Lisa M., et al.
Publicado: (2019)

A Case of Glucocorticoid Remediable Aldosteronism and Thoracoabdominal Aneurysms
por: Shahrrava, Anahita, et al.
Publicado: (2016)

Prophylactic and Early Thyroidectomy in RET Germline Mutation Carriers in Pediatric and Adult Population: Long-Term Outcomes of a Series of 63 Patients
por: Torresan, Francesca, et al.
Publicado: (2022)

Glucocorticoids promote CCL20 expression in keratinocytes
por: Wang, L., et al.
Publicado: (2021)

Keratinocytes control skin immune homeostasis through de novo–synthesized glucocorticoids
por: Phan, Truong San, et al.
Publicado: (2021)

Angiotensin II Promotes SARS-CoV-2 Infection via Upregulation of ACE2 in Human Bronchial Cells
por: Caputo, Ilaria, et al.
Publicado: (2022)

Defective glucocorticoid receptor signaling and keratinocyte-autonomous defects contribute to skin phenotype of mouse embryos lacking the Hsp90 co-chaperone p23
por: Madon-Simon, Marta, et al.
Publicado: (2017)

Aldosterone induces clonal β-cell failure through glucocorticoid receptor
por: Chen, Fang, et al.
Publicado: (2015)

Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism
por: Arlt, Wiebke, et al.
Publicado: (2017)

The Glucocorticoid Receptor is Required for Efficient Aldosterone-Induced Transcription by the Mineralocorticoid Receptor.
por: Johnson, Thomas A., et al.
Publicado: (2023)

Quantitative Value of Aldosterone‐Renin Ratio for Detection of Aldosterone‐Producing Adenoma: The Aldosterone‐Renin Ratio for Primary Aldosteronism (AQUARR) Study
por: Maiolino, Giuseppe, et al.
Publicado: (2017)

Glucocorticoid Resistance: Interference between the Glucocorticoid Receptor and the MAPK Signalling Pathways
por: Sevilla, Lisa M., et al.
Publicado: (2021)

Glucocorticoid Receptor Localizes to Adherens Junctions at the Plasma Membrane of Keratinocytes
por: Stojadinovic, Olivera, et al.
Publicado: (2013)

High Blood Pressure Is Associated with Tubulointerstitial Damage along with Glomerular Damage in Glomerulonephritis. A large Cohort Study
por: Bazzi, Claudio, et al.
Publicado: (2020)

Long-Term Outcomes after Surgery for Pheochromocytoma and Sympathetic Paraganglioma
por: Torresan, Francesca, et al.
Publicado: (2023)

Overexpression of L-Type Amino Acid Transporter 1 (LAT1) and 2 (LAT2): Novel Markers of Neuroendocrine Tumors
por: Barollo, Susi, et al.
Publicado: (2016)

Circulating miRNA Expression Profiling in Primary Aldosteronism
por: Decmann, Abel, et al.
Publicado: (2019)

Knockout of the Glucocorticoid Receptor Impairs Reproduction in Female Zebrafish
por: Maradonna, Francesca, et al.
Publicado: (2020)

The association of primary aldosteronism with glaucoma-related fundus abnormalities
por: Ohshima, Yoshimi, et al.
Publicado: (2020)

Glucocorticoid‐remediable aldosteronism in a young adult with a family history of Conn's syndrome
por: Methe, Heiko, et al.
Publicado: (2018)

MON-193 Glucocorticoid Excess and Its Association with Metabolic and Cardiovascular Complications in Primary Aldosteronism
por: zhu, Ke ying, et al.
Publicado: (2020)

Confirmation of Feasibility of Selective Glucocorticoid Replacement Following Unilateral Adrenalectomy for Hypercortisolism and Primary Aldosteronism
por: DeLozier, Olivia Mallory, et al.
Publicado: (2021)

FRI164 The Glucocorticoid Receptor is Required for Efficient Aldosterone-induced Transcription by the Mineralocorticoid Receptor
por: Johnson, Thomas A, et al.
Publicado: (2023)

FRI190 Catching A Chimera: A Case Of Suspected Glucocorticoid Remediable Aldosteronism
por: Khan, Aysha, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2amtvlepcj15419o917j198o9m