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Aliskiren Improves Ischemia- and Oxygen Glucose Deprivation-Induced Cardiac Injury through Activation of Autophagy and AMP-Activated Protein Kinase

Aliskiren is a direct renin inhibitor that has been effective in anti-hypertension. We investigated whether aliskiren could improve the ischemia-induced cardiac injury and whether the autophagy was involved in this effect. A myocardial infarction (MI) model was created by the ligation of the left an...

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Detalles Bibliográficos
Autores principales:	Chiang, Ming-Hsien, Liang, Chan-Jung, Liu, Chen-Wei, Pan, Bo-Jhih, Chen, Wen-Ping, Yang, Yi-Fan, Lee, I-Ta, Tsai, Jaw-Shiun, Lee, Chiang-Wen, Chen, Yuh-Lien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694452/ https://www.ncbi.nlm.nih.gov/pubmed/29184499 http://dx.doi.org/10.3389/fphar.2017.00819

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