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Novel Two-Step Classifier for Torsades de Pointes Risk Stratification from Direct Features
While pre-clinical Torsades de Pointes (TdP) risk classifiers had initially been based on drug-induced block of hERG potassium channels, it is now well established that improved risk prediction can be achieved by considering block of non-hERG ion channels. The current multi-channel TdP classifiers c...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694470/ https://www.ncbi.nlm.nih.gov/pubmed/29184497 http://dx.doi.org/10.3389/fphar.2017.00816 |