Influence of Morbid Obesity on the Pharmacokinetics of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide

INTRODUCTION: Obesity is associated with many pathophysiological changes that may result in altered drug metabolism. The aim of this study is to investigate the influence of obesity on the pharmacokinetics of morphine, morphine-3-glucuronide (M3G), and morphine-6-glucuronide (M6G) through a combined...

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Detalles Bibliográficos
Autores principales: de Hoogd, Sjoerd, Välitalo, Pyry A. J., Dahan, Albert, van Kralingen, Simone, Coughtrie, Michael M. W., van Dongen, Eric P. A., van Ramshorst, Bert, Knibbe, Catherijne A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694499/
https://www.ncbi.nlm.nih.gov/pubmed/28510797
http://dx.doi.org/10.1007/s40262-017-0544-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694499/
https://www.ncbi.nlm.nih.gov/pubmed/28510797
http://dx.doi.org/10.1007/s40262-017-0544-2

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