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Copper (II) complexes of bidentate ligands exhibit potent anti-cancer activity regardless of platinum sensitivity status

Insensitivity to platinum, either through inherent or acquired resistance, is a major clinical problem in the treatment of many solid tumors. Here, we explored the therapeutic potential of diethyldithiocarbamate (DDC), pyrithione (Pyr), plumbagin (Plum), 8-hydroxyquinoline (8-HQ), clioquinol (CQ) co...

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Detalles Bibliográficos
Autores principales:	Wehbe, Mohamed, Lo, Cody, Leung, Ada W. Y., Dragowska, Wieslawa H., Ryan, Gemma M., Bally, Marcel B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2017
Materias:	Preclinical Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694505/ https://www.ncbi.nlm.nih.gov/pubmed/28733701 http://dx.doi.org/10.1007/s10637-017-0488-2

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