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Analysis of Nausea in Clinical Studies of Lubiprostone for the Treatment of Constipation Disorders
BACKGROUND: Lubiprostone is a ClC-2 chloride channel activator approved for the treatment of chronic idiopathic constipation (CIC) and opioid-induced constipation (OIC) in adults and irritable bowel syndrome with constipation (IBS-C) in women. Lubiprostone is generally well tolerated, with nausea be...
Autores principales: | Cryer, Byron, Drossman, Douglas A., Chey, William D., Webster, Lynn, Habibi, Sepideh, Wang, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694526/ https://www.ncbi.nlm.nih.gov/pubmed/28849329 http://dx.doi.org/10.1007/s10620-017-4680-1 |
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