Kir2.1-Nav1.5 Channel Complexes Are Differently Regulated than Kir2.1 and Nav1.5 Channels Alone

Cardiac Kir2.1 and Nav1.5 channels generate the inward rectifier K(+) (I(K1)) and the Na(+) (I(Na)) currents, respectively. There is a mutual interplay between the ventricular I(Na) and I(K1) densities, because Nav1.5 and Kir2.1 channels exhibit positive reciprocal modulation. Here we compared some...

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Detalles Bibliográficos
Autores principales: Utrilla, Raquel G., Nieto-Marín, Paloma, Alfayate, Silvia, Tinaquero, David, Matamoros, Marcos, Pérez-Hernández, Marta, Sacristán, Sandra, Ondo, Lorena, de Andrés, Raquel, Díez-Guerra, F. Javier, Tamargo, Juan, Delpón, Eva, Caballero, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694551/
https://www.ncbi.nlm.nih.gov/pubmed/29184507
http://dx.doi.org/10.3389/fphys.2017.00903

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