A Concise Review on the Use of Mesenchymal Stem Cells in Cell Sheet-Based Tissue Engineering with Special Emphasis on Bone Tissue Regeneration

The integration of stem cell technology and cell sheet engineering improved the potential use of cell sheet products in regenerative medicine. This review will discuss the use of mesenchymal stem cells (MSCs) in cell sheet-based tissue engineering. Besides their adhesiveness to plastic surfaces and...

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Autores principales: Yorukoglu, A. Cagdas, Kiter, A. Esat, Akkaya, Semih, Satiroglu-Tufan, N. Lale, Tufan, A. Cevik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694585/
https://www.ncbi.nlm.nih.gov/pubmed/29230248
http://dx.doi.org/10.1155/2017/2374161
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author Yorukoglu, A. Cagdas
Kiter, A. Esat
Akkaya, Semih
Satiroglu-Tufan, N. Lale
Tufan, A. Cevik
author_facet Yorukoglu, A. Cagdas
Kiter, A. Esat
Akkaya, Semih
Satiroglu-Tufan, N. Lale
Tufan, A. Cevik
author_sort Yorukoglu, A. Cagdas
collection PubMed
description The integration of stem cell technology and cell sheet engineering improved the potential use of cell sheet products in regenerative medicine. This review will discuss the use of mesenchymal stem cells (MSCs) in cell sheet-based tissue engineering. Besides their adhesiveness to plastic surfaces and their extensive differentiation potential in vitro, MSCs are easily accessible, expandable in vitro with acceptable genomic stability, and few ethical issues. With all these advantages, they are extremely well suited for cell sheet-based tissue engineering. This review will focus on the use of MSC sheets in osteogenic tissue engineering. Potential application techniques with or without scaffolds and/or grafts will be discussed. Finally, the importance of osteogenic induction of these MSC sheets in orthopaedic applications will be demonstrated.
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spelling pubmed-56945852017-12-11 A Concise Review on the Use of Mesenchymal Stem Cells in Cell Sheet-Based Tissue Engineering with Special Emphasis on Bone Tissue Regeneration Yorukoglu, A. Cagdas Kiter, A. Esat Akkaya, Semih Satiroglu-Tufan, N. Lale Tufan, A. Cevik Stem Cells Int Review Article The integration of stem cell technology and cell sheet engineering improved the potential use of cell sheet products in regenerative medicine. This review will discuss the use of mesenchymal stem cells (MSCs) in cell sheet-based tissue engineering. Besides their adhesiveness to plastic surfaces and their extensive differentiation potential in vitro, MSCs are easily accessible, expandable in vitro with acceptable genomic stability, and few ethical issues. With all these advantages, they are extremely well suited for cell sheet-based tissue engineering. This review will focus on the use of MSC sheets in osteogenic tissue engineering. Potential application techniques with or without scaffolds and/or grafts will be discussed. Finally, the importance of osteogenic induction of these MSC sheets in orthopaedic applications will be demonstrated. Hindawi 2017 2017-11-05 /pmc/articles/PMC5694585/ /pubmed/29230248 http://dx.doi.org/10.1155/2017/2374161 Text en Copyright © 2017 A. Cagdas Yorukoglu et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Yorukoglu, A. Cagdas
Kiter, A. Esat
Akkaya, Semih
Satiroglu-Tufan, N. Lale
Tufan, A. Cevik
A Concise Review on the Use of Mesenchymal Stem Cells in Cell Sheet-Based Tissue Engineering with Special Emphasis on Bone Tissue Regeneration
title A Concise Review on the Use of Mesenchymal Stem Cells in Cell Sheet-Based Tissue Engineering with Special Emphasis on Bone Tissue Regeneration
title_full A Concise Review on the Use of Mesenchymal Stem Cells in Cell Sheet-Based Tissue Engineering with Special Emphasis on Bone Tissue Regeneration
title_fullStr A Concise Review on the Use of Mesenchymal Stem Cells in Cell Sheet-Based Tissue Engineering with Special Emphasis on Bone Tissue Regeneration
title_full_unstemmed A Concise Review on the Use of Mesenchymal Stem Cells in Cell Sheet-Based Tissue Engineering with Special Emphasis on Bone Tissue Regeneration
title_short A Concise Review on the Use of Mesenchymal Stem Cells in Cell Sheet-Based Tissue Engineering with Special Emphasis on Bone Tissue Regeneration
title_sort concise review on the use of mesenchymal stem cells in cell sheet-based tissue engineering with special emphasis on bone tissue regeneration
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694585/
https://www.ncbi.nlm.nih.gov/pubmed/29230248
http://dx.doi.org/10.1155/2017/2374161
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