Cargando…

Zinc transporters and insulin resistance: therapeutic implications for type 2 diabetes and metabolic disease

BACKGROUND: Zinc is a metal ion that is essential for growth and development, immunity, and metabolism, and therefore vital for life. Recent studies have highlighted zinc’s dynamic role as an insulin mimetic and a cellular second messenger that controls many processes associated with insulin signali...

Descripción completa

Detalles Bibliográficos
Autores principales:	Norouzi, Shaghayegh, Adulcikas, John, Sohal, Sukhwinder Singh, Myers, Stephen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694903/ https://www.ncbi.nlm.nih.gov/pubmed/29157234 http://dx.doi.org/10.1186/s12929-017-0394-0

Ejemplares similares

Targeting the Zinc Transporter ZIP7 in the Treatment of Insulin Resistance and Type 2 Diabetes
por: Adulcikas, John, et al.
Publicado: (2019)

The Zinc Transporter Zip7 Is Downregulated in Skeletal Muscle of Insulin-Resistant Cells and in Mice Fed a High-Fat Diet
por: Norouzi, Shaghayegh, et al.
Publicado: (2019)

Zinc stimulates glucose oxidation and glycemic control by modulating the insulin signaling pathway in human and mouse skeletal muscle cell lines
por: Norouzi, Shaghayegh, et al.
Publicado: (2018)

Zinc Modulates Several Transcription-Factor Regulated Pathways in Mouse Skeletal Muscle Cells
por: Vahidi Ferdowsi, Parisa, et al.
Publicado: (2020)

Zinc Transporters, Mechanisms of Action and Therapeutic Utility: Implications for Type 2 Diabetes Mellitus
por: Myers, Stephen A., et al.
Publicado: (2012)

Zinc Transporters and Zinc Signaling: New Insights into Their Role in Type 2 Diabetes
por: Myers, Stephen A.
Publicado: (2015)

Epithelial–mesenchymal transition is driven by transcriptional and post transcriptional modulations in COPD: implications for disease progression and new therapeutics
por: Eapen, Mathew Suji, et al.
Publicado: (2019)

Therapeutic Modalities for Asthma, COPD, and Pathogenesis of COVID-19: Insights from the Special Issue
por: Sohal, Sukhwinder Singh
Publicado: (2022)

Capsaicin and Zinc Signalling Pathways as Promising Targets for Managing Insulin Resistance and Type 2 Diabetes
por: Ferdowsi, Parisa Vahidi, et al.
Publicado: (2023)

Type-2 Diabetes as a Risk Factor for Severe COVID-19 Infection
por: Norouzi, Mahnaz, et al.
Publicado: (2021)

Obesity, Insulin Resistance, and Type 2 Diabetes: Associations and Therapeutic Implications
por: Wondmkun, Yohannes Tsegyie
Publicado: (2020)

WNT/β-catenin pathway: A novel therapeutic target for attenuating airway remodelling and EMT in COPD
por: Eapen, Mathew Suji, et al.
Publicado: (2020)

Essential need for rethink of COPD airway pathology: implications for new drug approaches for prevention of lung cancer as well as small airway fibrosis
por: Sohal, Sukhwinder Singh, et al.
Publicado: (2017)

Implications of the second wave of COVID-19 in India
por: Asrani, Purva, et al.
Publicado: (2021)

Endothelial to mesenchymal transition (EndMT): an active process in Chronic Obstructive Pulmonary Disease (COPD)?
por: Sohal, Sukhwinder Singh
Publicado: (2016)

Chronic Obstructive Pulmonary Disease (COPD) and Lung Cancer: Epithelial Mesenchymal Transition (EMT), the Missing Link?
por: Sohal, Sukhwinder Singh
Publicado: (2015)

Fluticasone propionate and increased risk of pneumonia in COPD: is it PAFR-dependent?
por: Sohal, Sukhwinder Singh
Publicado: (2017)

The Zinc Transporter, Slc39a7 (Zip7) Is Implicated in Glycaemic Control in Skeletal Muscle Cells
por: Myers, Stephen A., et al.
Publicado: (2013)

microRNAs Are Key Regulators in Chronic Lung Disease: Exploring the Vital Link between Disease Progression and Lung Cancer
por: Eapen, Mathew Suji, et al.
Publicado: (2019)

Diabetes, obesity, and insulin resistance in COVID-19: molecular interrelationship and therapeutic implications
por: Santos, Andrey, et al.
Publicado: (2021)

Therapeutic Targeting of Regulated Signaling Pathways of Non-Small Cell Lung Carcinoma
por: Hasan, Gulam Mustafa, et al.
Publicado: (2023)

Role of epithelial mesenchymal transition (EMT) in chronic obstructive pulmonary disease (COPD)
por: Sohal, Sukhwinder Singh, et al.
Publicado: (2013)

Epithelial mesenchymal transition (EMT) in small airways of COPD patients
por: Sohal, Sukhwinder Singh, et al.
Publicado: (2013)

Metabolic signature of obesity-associated insulin resistance and type 2 diabetes
por: Al-Sulaiti, Haya, et al.
Publicado: (2019)

ERBB3: A potential serum biomarker for early detection and therapeutic target for devil facial tumour 1 (DFT1)
por: Hayes, Dane A., et al.
Publicado: (2017)

Clinical Application of Forced Oscillation Technique (FOT) in Early Detection of Airway Changes in Smokers
por: Bhattarai, Prem, et al.
Publicado: (2020)

Insulin resistance and coronary artery disease in non-diabetic patients: Is there any correlation?
por: Vafaeimanesh, Jamshid, et al.
Publicado: (2018)

Posttranscriptional Regulation of Insulin Resistance: Implications for Metabolic Diseases
por: Pérez-García, Ana, et al.
Publicado: (2022)

Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes–Associated Variants
por: Nicolson, Tamara J., et al.
Publicado: (2009)

Effect of zinc supplementation on insulin resistance and metabolic risk factors in obese Korean women
por: Kim, Jihye, et al.
Publicado: (2012)

Electronic Cigarette Aerosol Is Cytotoxic and Increases ACE2 Expression on Human Airway Epithelial Cells: Implications for SARS-CoV-2 (COVID-19)
por: McAlinden, Kielan Darcy, et al.
Publicado: (2021)

An Insulin-Like Modular Basis for the Evolution of Glucose Transporters (GLUT) with Implications for Diabetes
por: Root-Bernstein, Robert
Publicado: (2007)

Type 2 Diabetes Mellitus and Alzheimer’s Disease: Role of Insulin Signalling and Therapeutic Implications
por: Tumminia, Andrea, et al.
Publicado: (2018)

Sarcopenic Obesity, Insulin Resistance, and Their Implications in Cardiovascular and Metabolic Consequences
por: Hong, So-hyeon, et al.
Publicado: (2020)

The involvement of aldosterone on vascular insulin resistance: implications in obesity and type 2 diabetes
por: Bruder-Nascimento, Thiago, et al.
Publicado: (2014)

Microbiota Modulating Nutritional Approaches to Countering the Effects of Viral Respiratory Infections Including SARS-CoV-2 through Promoting Metabolic and Immune Fitness with Probiotics and Plant Bioactives
por: Shinde, Tanvi, et al.
Publicado: (2020)

Zinc and Zinc Transporters in Dermatology
por: Al-Khafaji, Zubaidah, et al.
Publicado: (2022)

Decreased Insulin-Stimulated ATP Synthesis and Phosphate Transport in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Parents
por: Petersen, Kitt F, et al.
Publicado: (2005)

Lipid metabolism in type 1 diabetes mellitus: Pathogenetic and therapeutic implications
por: Zhang, Jing, et al.
Publicado: (2022)

β-Cell Expansion for Therapeutic Compensation of Insulin Resistance in Type 2 Diabetes
por: Efrat, Shimon
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_q1pitjhe7fpujiijrqh61qca8i