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Viral Hepatitis Endemicity and Trends among an Asymptomatic Adult Population in Ho: A 5-Year Retrospective Study at the Ho Municipal Hospital, Ghana

BACKGROUND: Using prospective blood donors as a proxy, this study was aimed at estimating the burden and five-year (2012–2016) trend of viral hepatitis (HBV and HCV) infection among asymptomatic adult population in Ho. MATERIALS AND METHODS: A retrospective analysis was done on secondary data extrac...

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Autores principales: Lokpo, Sylvester Yao, Osei-Yeboah, James, Norgbe, Gameli Kwame, Owiafe, Patrick Kwasi, Ayroe, Felix, Ussher, Francis Abeku, Dakorah, Mavis Popuelle, Gameli Deku, John, Manaphraim, Nana Yaw Barimah, Akomanin Asiamah, Emmanuel, Ntoni, Tibemponi, Senyo Kwasi Nyamadi, Prince, Yiadom Boakye, Edward, Avorkliyah, Roseline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694981/
https://www.ncbi.nlm.nih.gov/pubmed/29234524
http://dx.doi.org/10.1155/2017/6174743
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author Lokpo, Sylvester Yao
Osei-Yeboah, James
Norgbe, Gameli Kwame
Owiafe, Patrick Kwasi
Ayroe, Felix
Ussher, Francis Abeku
Dakorah, Mavis Popuelle
Gameli Deku, John
Manaphraim, Nana Yaw Barimah
Akomanin Asiamah, Emmanuel
Ntoni, Tibemponi
Senyo Kwasi Nyamadi, Prince
Yiadom Boakye, Edward
Avorkliyah, Roseline
author_facet Lokpo, Sylvester Yao
Osei-Yeboah, James
Norgbe, Gameli Kwame
Owiafe, Patrick Kwasi
Ayroe, Felix
Ussher, Francis Abeku
Dakorah, Mavis Popuelle
Gameli Deku, John
Manaphraim, Nana Yaw Barimah
Akomanin Asiamah, Emmanuel
Ntoni, Tibemponi
Senyo Kwasi Nyamadi, Prince
Yiadom Boakye, Edward
Avorkliyah, Roseline
author_sort Lokpo, Sylvester Yao
collection PubMed
description BACKGROUND: Using prospective blood donors as a proxy, this study was aimed at estimating the burden and five-year (2012–2016) trend of viral hepatitis (HBV and HCV) infection among asymptomatic adult population in Ho. MATERIALS AND METHODS: A retrospective analysis was done on secondary data extracted from the hospital archives comprising 4,180 prospective blood donors from January 2012 to December 2016. Demographic variables included age and sex, as well as place of residence. Screening results of serum infectious markers (HBV and HCV) were obtained. RESULTS: The prevalence of asymptomatic viral hepatitis (HBV and HCV) infection in the general adult population was 6.94% and 1.84%, respectively. Females recorded a higher burden of HBV and HCV (8.3% and 5.0%) compared to their male peers (6.8% and 1.4%). A significant age variation in HBV antigenaemia was seen with HBV seropositivity peaking among the younger population (less than 20 years' group) at 11.24% and troughed among the older population (above 50 years' group) at 0.92%. CONCLUSION: Asymptomatic viral hepatitis among adult population in the Ho Municipality is estimated at the intermediate to high endemicity level. Preventive measures to reduce the burden are urgently needed and should be targeted at the younger generation.
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spelling pubmed-56949812017-12-11 Viral Hepatitis Endemicity and Trends among an Asymptomatic Adult Population in Ho: A 5-Year Retrospective Study at the Ho Municipal Hospital, Ghana Lokpo, Sylvester Yao Osei-Yeboah, James Norgbe, Gameli Kwame Owiafe, Patrick Kwasi Ayroe, Felix Ussher, Francis Abeku Dakorah, Mavis Popuelle Gameli Deku, John Manaphraim, Nana Yaw Barimah Akomanin Asiamah, Emmanuel Ntoni, Tibemponi Senyo Kwasi Nyamadi, Prince Yiadom Boakye, Edward Avorkliyah, Roseline Hepat Res Treat Research Article BACKGROUND: Using prospective blood donors as a proxy, this study was aimed at estimating the burden and five-year (2012–2016) trend of viral hepatitis (HBV and HCV) infection among asymptomatic adult population in Ho. MATERIALS AND METHODS: A retrospective analysis was done on secondary data extracted from the hospital archives comprising 4,180 prospective blood donors from January 2012 to December 2016. Demographic variables included age and sex, as well as place of residence. Screening results of serum infectious markers (HBV and HCV) were obtained. RESULTS: The prevalence of asymptomatic viral hepatitis (HBV and HCV) infection in the general adult population was 6.94% and 1.84%, respectively. Females recorded a higher burden of HBV and HCV (8.3% and 5.0%) compared to their male peers (6.8% and 1.4%). A significant age variation in HBV antigenaemia was seen with HBV seropositivity peaking among the younger population (less than 20 years' group) at 11.24% and troughed among the older population (above 50 years' group) at 0.92%. CONCLUSION: Asymptomatic viral hepatitis among adult population in the Ho Municipality is estimated at the intermediate to high endemicity level. Preventive measures to reduce the burden are urgently needed and should be targeted at the younger generation. Hindawi 2017 2017-11-06 /pmc/articles/PMC5694981/ /pubmed/29234524 http://dx.doi.org/10.1155/2017/6174743 Text en Copyright © 2017 Sylvester Yao Lokpo et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Lokpo, Sylvester Yao
Osei-Yeboah, James
Norgbe, Gameli Kwame
Owiafe, Patrick Kwasi
Ayroe, Felix
Ussher, Francis Abeku
Dakorah, Mavis Popuelle
Gameli Deku, John
Manaphraim, Nana Yaw Barimah
Akomanin Asiamah, Emmanuel
Ntoni, Tibemponi
Senyo Kwasi Nyamadi, Prince
Yiadom Boakye, Edward
Avorkliyah, Roseline
Viral Hepatitis Endemicity and Trends among an Asymptomatic Adult Population in Ho: A 5-Year Retrospective Study at the Ho Municipal Hospital, Ghana
title Viral Hepatitis Endemicity and Trends among an Asymptomatic Adult Population in Ho: A 5-Year Retrospective Study at the Ho Municipal Hospital, Ghana
title_full Viral Hepatitis Endemicity and Trends among an Asymptomatic Adult Population in Ho: A 5-Year Retrospective Study at the Ho Municipal Hospital, Ghana
title_fullStr Viral Hepatitis Endemicity and Trends among an Asymptomatic Adult Population in Ho: A 5-Year Retrospective Study at the Ho Municipal Hospital, Ghana
title_full_unstemmed Viral Hepatitis Endemicity and Trends among an Asymptomatic Adult Population in Ho: A 5-Year Retrospective Study at the Ho Municipal Hospital, Ghana
title_short Viral Hepatitis Endemicity and Trends among an Asymptomatic Adult Population in Ho: A 5-Year Retrospective Study at the Ho Municipal Hospital, Ghana
title_sort viral hepatitis endemicity and trends among an asymptomatic adult population in ho: a 5-year retrospective study at the ho municipal hospital, ghana
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694981/
https://www.ncbi.nlm.nih.gov/pubmed/29234524
http://dx.doi.org/10.1155/2017/6174743
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