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New genes often acquire male-specific functions but rarely become essential in Drosophila

Relatively little is known about the in vivo functions of newly emerging genes, especially in metazoans. Although prior RNAi studies reported prevalent lethality among young gene knockdowns, our phylogenomic analyses reveal that young Drosophila genes are frequently restricted to the nonessential ma...

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Detalles Bibliográficos
Autores principales: Kondo, Shu, Vedanayagam, Jeffrey, Mohammed, Jaaved, Eizadshenass, Sogol, Kan, Lijuan, Pang, Nan, Aradhya, Rajaguru, Siepel, Adam, Steinhauer, Josefa, Lai, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695085/
https://www.ncbi.nlm.nih.gov/pubmed/29051389
http://dx.doi.org/10.1101/gad.303131.117