Salmonella Utilizes Zinc To Subvert Antimicrobial Host Defense of Macrophages via Modulation of NF-κB Signaling

Zinc sequestration by macrophages is considered a crucial host defense strategy against infection by the intracellular bacterium Salmonella enterica serovar Typhimurium. However, the underlying mechanisms remain elusive. In this study, we found that zinc favors pathogen survival within macrophages....

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Detalles Bibliográficos
Autores principales: Wu, Aimin, Tymoszuk, Piotr, Haschka, David, Heeke, Simon, Dichtl, Stefanie, Petzer, Verena, Seifert, Markus, Hilbe, Richard, Sopper, Sieghart, Talasz, Heribert, Bumann, Dirk, Lass-Flörl, Cornelia, Theurl, Igor, Zhang, Keying, Weiss, Guenter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695101/
https://www.ncbi.nlm.nih.gov/pubmed/28874447
http://dx.doi.org/10.1128/IAI.00418-17

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