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Longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging

We present two patients with three‐vessel disease and severely depressed left ventricular (LV) systolic function where viability analysis by cardiac magnetic resonance imaging demonstrated areas of near‐transmural sub‐endocardial fibrosis and hence little chance of regaining systolic function as jud...

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Autores principales: Bjerre, Jenny, Kyhl, Kasper, Gustafsson, Finn, Kelbæk, Henning, Engstrøm, Thomas, Olsen, Peter Skov, Hasbak, Philip, Vejlstrup, Niels, Madsen, Per Lav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695176/
https://www.ncbi.nlm.nih.gov/pubmed/29030924
http://dx.doi.org/10.1002/ehf2.12187
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author Bjerre, Jenny
Kyhl, Kasper
Gustafsson, Finn
Kelbæk, Henning
Engstrøm, Thomas
Olsen, Peter Skov
Hasbak, Philip
Vejlstrup, Niels
Madsen, Per Lav
author_facet Bjerre, Jenny
Kyhl, Kasper
Gustafsson, Finn
Kelbæk, Henning
Engstrøm, Thomas
Olsen, Peter Skov
Hasbak, Philip
Vejlstrup, Niels
Madsen, Per Lav
author_sort Bjerre, Jenny
collection PubMed
description We present two patients with three‐vessel disease and severely depressed left ventricular (LV) systolic function where viability analysis by cardiac magnetic resonance imaging demonstrated areas of near‐transmural sub‐endocardial fibrosis and hence little chance of regaining systolic function as judged by conventional analysis from radial function. Despite the pessimistic cardiac magnetic resonance imaging analysis, however, the patients underwent full revascularization and regained impressive increases in LV systolic function mainly based on improved longitudinal systolic segment function. The cases highlight that sub‐epicardial, longitudinally oriented myocytes can contribute to overall LV systolic function and suggest taking their ‘piston‐function’ into consideration when analysing viability.
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spelling pubmed-56951762018-02-14 Longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging Bjerre, Jenny Kyhl, Kasper Gustafsson, Finn Kelbæk, Henning Engstrøm, Thomas Olsen, Peter Skov Hasbak, Philip Vejlstrup, Niels Madsen, Per Lav ESC Heart Fail Case Reports We present two patients with three‐vessel disease and severely depressed left ventricular (LV) systolic function where viability analysis by cardiac magnetic resonance imaging demonstrated areas of near‐transmural sub‐endocardial fibrosis and hence little chance of regaining systolic function as judged by conventional analysis from radial function. Despite the pessimistic cardiac magnetic resonance imaging analysis, however, the patients underwent full revascularization and regained impressive increases in LV systolic function mainly based on improved longitudinal systolic segment function. The cases highlight that sub‐epicardial, longitudinally oriented myocytes can contribute to overall LV systolic function and suggest taking their ‘piston‐function’ into consideration when analysing viability. John Wiley and Sons Inc. 2017-10-13 /pmc/articles/PMC5695176/ /pubmed/29030924 http://dx.doi.org/10.1002/ehf2.12187 Text en © 2017 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Bjerre, Jenny
Kyhl, Kasper
Gustafsson, Finn
Kelbæk, Henning
Engstrøm, Thomas
Olsen, Peter Skov
Hasbak, Philip
Vejlstrup, Niels
Madsen, Per Lav
Longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging
title Longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging
title_full Longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging
title_fullStr Longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging
title_full_unstemmed Longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging
title_short Longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging
title_sort longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695176/
https://www.ncbi.nlm.nih.gov/pubmed/29030924
http://dx.doi.org/10.1002/ehf2.12187
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