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Longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging
We present two patients with three‐vessel disease and severely depressed left ventricular (LV) systolic function where viability analysis by cardiac magnetic resonance imaging demonstrated areas of near‐transmural sub‐endocardial fibrosis and hence little chance of regaining systolic function as jud...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695176/ https://www.ncbi.nlm.nih.gov/pubmed/29030924 http://dx.doi.org/10.1002/ehf2.12187 |
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author | Bjerre, Jenny Kyhl, Kasper Gustafsson, Finn Kelbæk, Henning Engstrøm, Thomas Olsen, Peter Skov Hasbak, Philip Vejlstrup, Niels Madsen, Per Lav |
author_facet | Bjerre, Jenny Kyhl, Kasper Gustafsson, Finn Kelbæk, Henning Engstrøm, Thomas Olsen, Peter Skov Hasbak, Philip Vejlstrup, Niels Madsen, Per Lav |
author_sort | Bjerre, Jenny |
collection | PubMed |
description | We present two patients with three‐vessel disease and severely depressed left ventricular (LV) systolic function where viability analysis by cardiac magnetic resonance imaging demonstrated areas of near‐transmural sub‐endocardial fibrosis and hence little chance of regaining systolic function as judged by conventional analysis from radial function. Despite the pessimistic cardiac magnetic resonance imaging analysis, however, the patients underwent full revascularization and regained impressive increases in LV systolic function mainly based on improved longitudinal systolic segment function. The cases highlight that sub‐epicardial, longitudinally oriented myocytes can contribute to overall LV systolic function and suggest taking their ‘piston‐function’ into consideration when analysing viability. |
format | Online Article Text |
id | pubmed-5695176 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-56951762018-02-14 Longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging Bjerre, Jenny Kyhl, Kasper Gustafsson, Finn Kelbæk, Henning Engstrøm, Thomas Olsen, Peter Skov Hasbak, Philip Vejlstrup, Niels Madsen, Per Lav ESC Heart Fail Case Reports We present two patients with three‐vessel disease and severely depressed left ventricular (LV) systolic function where viability analysis by cardiac magnetic resonance imaging demonstrated areas of near‐transmural sub‐endocardial fibrosis and hence little chance of regaining systolic function as judged by conventional analysis from radial function. Despite the pessimistic cardiac magnetic resonance imaging analysis, however, the patients underwent full revascularization and regained impressive increases in LV systolic function mainly based on improved longitudinal systolic segment function. The cases highlight that sub‐epicardial, longitudinally oriented myocytes can contribute to overall LV systolic function and suggest taking their ‘piston‐function’ into consideration when analysing viability. John Wiley and Sons Inc. 2017-10-13 /pmc/articles/PMC5695176/ /pubmed/29030924 http://dx.doi.org/10.1002/ehf2.12187 Text en © 2017 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Case Reports Bjerre, Jenny Kyhl, Kasper Gustafsson, Finn Kelbæk, Henning Engstrøm, Thomas Olsen, Peter Skov Hasbak, Philip Vejlstrup, Niels Madsen, Per Lav Longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging |
title | Longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging |
title_full | Longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging |
title_fullStr | Longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging |
title_full_unstemmed | Longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging |
title_short | Longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging |
title_sort | longitudinal shortening of sub‐epicardial myocytes in severe ischaemic cardiomyopathy: insights from gadolinium contrast cardiac magnetic resonance imaging |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695176/ https://www.ncbi.nlm.nih.gov/pubmed/29030924 http://dx.doi.org/10.1002/ehf2.12187 |
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