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Insight into the interactions, residue snorkeling, and membrane disordering potency of a single antimicrobial peptide into different lipid bilayers

Pardaxin, with a bend-helix-bend-helix structure, is a membrane-active antimicrobial peptide that its membrane activity depends on the lipid bilayer composition. Herein, all-atom molecular dynamics (MD) simulations were performed to provide further molecular insight into the interactions, structural...

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Detalles Bibliográficos
Autores principales: Jafari, Majid, Mehrnejad, Faramarz, Doustdar, Farahnoosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695277/
https://www.ncbi.nlm.nih.gov/pubmed/29125878
http://dx.doi.org/10.1371/journal.pone.0187216

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