Cargando…

Are objective measures of physical capability related to accelerated epigenetic age? Findings from a British birth cohort

OBJECTIVES: Our aim was to investigate the association of epigenetic age and physical capability in later life. Having a higher epigenetic than chronological age (known as age acceleration (AA)) has been found to be associated with an increased rate of mortality. Similarly, physical capability has b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Simpkin, Andrew J, Cooper, Rachel, Howe, Laura D, Relton, Caroline L, Davey Smith, George, Teschendorff, Andrew, Widschwendter, Martin, Wong, Andrew, Kuh, Diana, Hardy, Rebecca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2017
Materias:	Epidemiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695310/ https://www.ncbi.nlm.nih.gov/pubmed/29092899 http://dx.doi.org/10.1136/bmjopen-2017-016708

Ejemplares similares

Psychosocial adversity and socioeconomic position during childhood and epigenetic age: analysis of two prospective cohort studies
por: Lawn, Rebecca B, et al.
Publicado: (2018)

Markers of pubertal timing and leisure-time physical activity from ages 36 to 68 years: findings from a British birth cohort
por: Elhakeem, Ahmed, et al.
Publicado: (2017)

Developmental factors associated with decline in grip strength from midlife to old age: a British birth cohort study
por: Kuh, Diana, et al.
Publicado: (2019)

Do the associations of body mass index and waist circumference with back pain change as people age? 32 years of follow-up in a British birth cohort
por: Muthuri, Stella, et al.
Publicado: (2020)

Objective Sedentary Time, Moderate-to-Vigorous Physical Activity, and Physical Capability in a British Cohort
por: KEEVIL, VICTORIA L., et al.
Publicado: (2016)

Lifelong socioeconomic position and physical performance in midlife: results from the British 1946 birth cohort
por: Strand, Bjørn Heine, et al.
Publicado: (2011)

Life course body mass index and risk of knee osteoarthritis at the age of 53 years: evidence from the 1946 British birth cohort study
por: Wills, Andrew K, et al.
Publicado: (2011)

Use of Correct and Incorrect Methods of Accounting for Age in Studies of Epigenetic Accelerated Aging: Implications and Recommendations for Best Practices
por: Krieger, Nancy, et al.
Publicado: (2023)

Job demand and control in mid-life and physical and mental functioning in early old age: do childhood factors explain these associations in a British birth cohort?
por: von Bonsdorff, Mikaela B, et al.
Publicado: (2014)

Physical Activity, Sedentary Time and Physical Capability in Early Old Age: British Birth Cohort Study
por: Cooper, Andrew J. M., et al.
Publicado: (2015)

Dietary calcium and vitamin D intakes in childhood and throughout adulthood and mammographic density in a British birth cohort
por: Mishra, G, et al.
Publicado: (2008)

Physical capability in mid-life and survival over 13 years of follow-up: British birth cohort study
por: Cooper, Rachel, et al.
Publicado: (2014)

Longitudinal analysis strategies for modelling epigenetic trajectories
por: Staley, James R, et al.
Publicado: (2018)

Life-course body size and perimenopausal mammographic parenchymal patterns in the MRC 1946 British birth cohort
por: McCormack, V A, et al.
Publicado: (2003)

Associations Between Polypharmacy and Cognitive and Physical Capability: A British Birth Cohort Study
por: Rawle, Mark James, et al.
Publicado: (2018)

Area Deprivation Across the Life Course and Physical Capability in Midlife: Findings From the 1946 British Birth Cohort
por: Murray, Emily T., et al.
Publicado: (2013)

Childhood Cognitive Ability and Age-Related Changes in Physical Capability From Midlife: Findings From a British Birth Cohort Study
por: Cooper, Rachel, et al.
Publicado: (2017)

Epigenetic gestational age acceleration: a prospective cohort study investigating associations with familial, sociodemographic and birth characteristics
por: Khouja, Jasmine N., et al.
Publicado: (2018)

Adiposity, Telomere Length, and Telomere Attrition in Midlife: the 1946 British Birth Cohort
por: Wulaningsih, Wahyu, et al.
Publicado: (2018)

Age at menopause and lifetime cognition: Findings from a British birth cohort study
por: Kuh, Diana, et al.
Publicado: (2018)

Associations of behavioural risk factors and health status with changes in physical capability over 10 years of follow-up: the MRC National Survey of Health and Development
por: Cooper, Rachel, et al.
Publicado: (2016)

Identifying the lifetime cognitive and socioeconomic antecedents of cognitive state: seven decades of follow-up in a British birth cohort study
por: Richards, M, et al.
Publicado: (2019)

Systemic Inflammation and Cardio-Renal Organ Damage Biomarkers in Middle Age Are Associated With Physical Capability Up to 9 Years Later: Findings From a British Birth Cohort Study
por: Kuh, Diana, et al.
Publicado: (2019)

Symptoms of anxiety and depression across adulthood and blood pressure in late middle age: the 1946 British birth cohort
por: Tikhonoff, Valérie, et al.
Publicado: (2014)

Challenges in examining area effects across the life course on physical capability in mid-life: Findings from the 1946 British Birth Cohort
por: Murray, Emily T., et al.
Publicado: (2012)

Objectively measured physical capability levels and mortality: systematic review and meta-analysis
por: Cooper, Rachel, et al.
Publicado: (2010)

Growth From Birth to Adulthood and Bone Phenotype in Early Old Age: A British Birth Cohort Study
por: Kuh, Diana, et al.
Publicado: (2014)

Parental age and offspring leukocyte telomere length and attrition in midlife: Evidence from the 1946 British birth cohort
por: Wulaningsih, Wahyu, et al.
Publicado: (2018)

Lifetime cognition and late midlife blood metabolites: findings from a British birth cohort
por: Proitsi, Petroula, et al.
Publicado: (2018)

Correlation of an epigenetic mitotic clock with cancer risk
por: Yang, Zhen, et al.
Publicado: (2016)

Lifetime socioeconomic circumstances and chronic pain in later adulthood: findings from a British birth cohort study
por: Jay, Matthew A, et al.
Publicado: (2019)

Validation of self-reported diagnosis of diabetes in the 1946 British birth cohort
por: Pastorino, Silvia, et al.
Publicado: (2015)

Stochastic epigenetic outliers can define field defects in cancer
por: Teschendorff, Andrew E., et al.
Publicado: (2016)

Objective measures of physical capability and subsequent health: a systematic review
por: Cooper, Rachel, et al.
Publicado: (2011)

The epigenetic clock and physical development during childhood and adolescence: longitudinal analysis from a UK birth cohort
por: Simpkin, Andrew J, et al.
Publicado: (2017)

Socioeconomic position across life and body composition in early old age: findings from a British birth cohort study
por: Bann, David, et al.
Publicado: (2014)

Smoking before the birth of a first child is not associated with increased risk of breast cancer: findings from the British Women's Heart and Health Cohort Study and a meta-analysis
por: Lawlor, D A, et al.
Publicado: (2004)

ARE THERE BIDIRECTIONAL ASSOCIATIONS BETWEEN COGNITION AND BALANCE ABILITY: EVIDENCE FROM A BRITISH BIRTH COHORT
por: Blodgett, Joanna M, et al.
Publicado: (2019)

Is the Hierarchy of Loss in Functional Ability Evident in Midlife? Findings from a British Birth Cohort
por: Wloch, Elizabeth G., et al.
Publicado: (2016)

Body mass index trajectories and age at menopause in a British birth cohort
por: Hardy, Rebecca, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_do4c5j1u1mveq75gpdpv80ohmk