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Bacillus anthracis lethal toxin negatively modulates ILC3 function through perturbation of IL-23-mediated MAPK signaling
Bacillus anthracis, the causative agent of anthrax, secretes lethal toxin that down-regulates immune functions. Translocation of B. anthracis across mucosal epithelia is key for its dissemination and pathogenesis. Group 3 innate lymphocytes (ILC3s) are important in mucosal barrier maintenance due to...
Autores principales: | Seshadri, Sudarshan, Allan, David S. J., Carlyle, James R., Zenewicz, Lauren A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695638/ https://www.ncbi.nlm.nih.gov/pubmed/29059238 http://dx.doi.org/10.1371/journal.ppat.1006690 |
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