Soluble CD40 ligand directly alters glomerular permeability and may act as a circulating permeability factor in FSGS

CD40/CD40 ligand (CD40L) dyad, a co-stimulatory bi-molecular complex involved in the adaptive immune response, has also potent pro-inflammatory actions in haematopoietic and non-haematopoietic cells. We describe here a novel role for soluble CD40L (sCD40L) as modifier of glomerular permselectivity d...

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Detalles Bibliográficos
Autores principales: Doublier, Sophie, Zennaro, Cristina, Musante, Luca, Spatola, Tiziana, Candiano, Giovanni, Bruschi, Maurizio, Besso, Luca, Cedrino, Massimo, Carraro, Michele, Ghiggeri, Gian Marco, Camussi, Giovanni, Lupia, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695800/
https://www.ncbi.nlm.nih.gov/pubmed/29155846
http://dx.doi.org/10.1371/journal.pone.0188045

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