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Reduced order modeling and analysis of the human complement system
Complement is an important pathway in innate immunity, inflammation, and many disease processes. However, despite its importance, there are few validated mathematical models of complement activation. In this study, we developed an ensemble of experimentally validated reduced order complement models....
Autores principales: | Sagar, Adithya, Dai, Wei, Minot, Mason, LeCover, Rachel, Varner, Jeffrey D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695804/ https://www.ncbi.nlm.nih.gov/pubmed/29155837 http://dx.doi.org/10.1371/journal.pone.0187373 |
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