Ghrelin protects against nucleus pulposus degeneration through inhibition of NF-κB signaling pathway and activation of Akt signaling pathway

The objective of the present study was to examine the potential role of ghrelin in degeneration of nucleus pulposus (NP). Lower expression levels of ghrelin were found in human NP cells stimulated with interleukin-1β (IL-1β). Moreover, exogenous ghrelin suppressed IL-1β induced degeneration and infl...

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Detalles Bibliográficos
Autores principales: Li, Weiwei, Wu, Xihai, Qu, Ruize, Wang, Wenhan, Chen, Xiaomin, Cheng, Lei, Liu, Yaoge, Guo, Linlin, Zhao, Yunpeng, Liu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696149/
https://www.ncbi.nlm.nih.gov/pubmed/29190883
http://dx.doi.org/10.18632/oncotarget.19695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696149/
https://www.ncbi.nlm.nih.gov/pubmed/29190883
http://dx.doi.org/10.18632/oncotarget.19695

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