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Ghrelin protects against nucleus pulposus degeneration through inhibition of NF-κB signaling pathway and activation of Akt signaling pathway
The objective of the present study was to examine the potential role of ghrelin in degeneration of nucleus pulposus (NP). Lower expression levels of ghrelin were found in human NP cells stimulated with interleukin-1β (IL-1β). Moreover, exogenous ghrelin suppressed IL-1β induced degeneration and infl...
Autores principales: | Li, Weiwei, Wu, Xihai, Qu, Ruize, Wang, Wenhan, Chen, Xiaomin, Cheng, Lei, Liu, Yaoge, Guo, Linlin, Zhao, Yunpeng, Liu, Chao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696149/ https://www.ncbi.nlm.nih.gov/pubmed/29190883 http://dx.doi.org/10.18632/oncotarget.19695 |
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