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Silibinin suppresses bladder cancer through down-regulation of actin cytoskeleton and PI3K/Akt signaling pathways
Silibinin is the major active constituent of silymarin, an extract of milk thistle seeds. Silibinin has been shown to have significant anti-cancer effects in a variety of malignancies. However, the molecular mechanisms of silibinin action in bladder cancer have not been studied extensively. In the p...
Autores principales: | Imai-Sumida, Mitsuho, Chiyomaru, Takeshi, Majid, Shahana, Saini, Sharanjot, Nip, Hannah, Dahiya, Rajvir, Tanaka, Yuichiro, Yamamura, Soichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696161/ https://www.ncbi.nlm.nih.gov/pubmed/29190895 http://dx.doi.org/10.18632/oncotarget.20734 |
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