Cargando…

Verrucarin J inhibits ovarian cancer and targets cancer stem cells

Ovarian Cancer is the fifth leading cause of death among women from cancer. Cancer stem cells are a small population of cells present in cancer and the cause of chemoresistance and recurrence of cancer. We tested a new compound “Verrucarin J (VJ)”, a metabolite of the Myrothecium fungus family, and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Carter, Kelsey, Rameshwar, Pranela, Ratajczak, Mariusz Z., Kakar, Sham S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696218/ https://www.ncbi.nlm.nih.gov/pubmed/29190952 http://dx.doi.org/10.18632/oncotarget.21574

Ejemplares similares

Withaferin A (WFA) inhibits tumor growth and metastasis by targeting ovarian cancer stem cells
por: Kakar, Sham S., et al.
Publicado: (2017)

Correction: Withaferin A (WFA) inhibits tumor growth and metastasis by targeting ovarian cancer stem cells
por: Kakar, Sham S., et al.
Publicado: (2020)

Bioactive Phospholipids Enhance Migration and Adhesion of Human Leukemic Cells by Inhibiting Heme Oxygenase 1 (HO-1) and Inducible Nitric Oxygenase Synthase (iNOS) in a p38 MAPK-Dependent Manner
por: Abdelbaset-Ismail, Ahmed, et al.
Publicado: (2018)

Exosomes: an overview of biogenesis, composition and role in ovarian cancer
por: Beach, Allison, et al.
Publicado: (2014)

Withaferin A Alone and in Combination with Cisplatin Suppresses Growth and Metastasis of Ovarian Cancer by Targeting Putative Cancer Stem Cells
por: Kakar, Sham S., et al.
Publicado: (2014)

Vitamin D3 stimulates embryonic stem cells but inhibits migration and growth of ovarian cancer and teratocarcinoma cell lines
por: Abdelbaset-Ismail, Ahmed, et al.
Publicado: (2016)

Suppression of Notch1 and AKT mediated epithelial to mesenchymal transition by Verrucarin J in metastatic colon cancer
por: Pal, Deeksha, et al.
Publicado: (2018)

Targeted Extracellular Vesicles Delivered Verrucarin A to Treat Glioblastoma
por: Chen, Kai, et al.
Publicado: (2022)

Commentary: FSH and various forms of FSH receptors: distribution and their functions in gonads and extra-gonadal tissues
por: Kakar, Sham S., et al.
Publicado: (2021)

Novel pleiotropic effects of bioactive phospholipids in human lung cancer metastasis
por: Schneider, Gabriela, et al.
Publicado: (2017)

Cancer stem cell gene profile getting closer to the clinic to enhance precise treatment
por: Rameshwar, Pranela
Publicado: (2019)

Evaluation of a developmental hierarchy for breast cancer cells to assess risk-based patient selection for targeted treatment
por: Bliss, Sarah A., et al.
Publicado: (2018)

Evidence for induction of a tumor metastasis-receptive microenvironment for ovarian cancer cells in bone marrow and other organs as an unwanted and underestimated side effect of chemotherapy/radiotherapy
por: Gunjal, Pranesh M, et al.
Publicado: (2015)

Verrucarin A Inhibition of MAP Kinase Activation in a PMA-stimulated Promyelocytic Leukemia Cell Line
por: Oda, Taiko, et al.
Publicado: (2005)

Stem Cells in Ovarian Cancer and Potential Therapies
por: Zuber, Elena, et al.
Publicado: (2020)

Characterization of stem cell and cancer stem cell populations in ovary and ovarian tumors
por: Parte, Seema C., et al.
Publicado: (2018)

PTTG: an important target gene for ovarian cancer therapy
por: Panguluri, Siva Kumar, et al.
Publicado: (2008)

Induction of a tumor-metastasis-receptive microenvironment as an unwanted and underestimated side effect of treatment by chemotherapy or radiotherapy
por: Ratajczak, Mariusz Z, et al.
Publicado: (2013)

Identification of Verrucarin A as a Potent and Selective Steroid Receptor Coactivator-3 Small Molecule Inhibitor
por: Yan, Fei, et al.
Publicado: (2014)

Inhibitory Effects of Verrucarin A on Tunicamycin-Induced ER Stress in FaO Rat Liver Cells
por: Bae, Eun Young, et al.
Publicado: (2015)

A Review of Stem Cell Translation and Potential Confounds by Cancer Stem Cells
por: Bibber, Bernadette, et al.
Publicado: (2013)

Ovarian cancer mouse models: a summary of current models and their limitations
por: Fong, Miranda Y, et al.
Publicado: (2009)

Withaferin A ameliorates ovarian cancer-induced cachexia and proinflammatory signaling
por: Straughn, Alex R., et al.
Publicado: (2019)

Inflammatory mediators: Parallels between cancer biology and stem cell therapy
por: Patel, Shyam A, et al.
Publicado: (2009)

Microenvironmental considerations in the application of human mesenchymal stem cells in regenerative therapies
por: Greco, Steven J, et al.
Publicado: (2008)

Multipotent to Pluripotent Properties of Adult Stem Cells
por: Bhartiya, Deepa, et al.
Publicado: (2013)

Withaferin A attenuates ovarian cancer-induced cardiac cachexia
por: Kelm, Natia Q., et al.
Publicado: (2020)

Expression of the erythropoietin receptor by germline-derived cells - further support for a potential developmental link between the germline and hematopoiesis
por: Suszynska, Malwina, et al.
Publicado: (2014)

The Immune Properties of Mesenchymal Stem Cells
por: Castillo, Marianne, et al.
Publicado: (2007)

Identification of Metabolites in the Normal Ovary and Their Transformation in Primary and Metastatic Ovarian Cancer
por: Fong, Miranda Y., et al.
Publicado: (2011)

Withaferin A and Ovarian Cancer Antagonistically Regulate Skeletal Muscle Mass
por: Straughn, Alex R., et al.
Publicado: (2021)

Breast Cancer Biology: The Multifaceted Roles of Mesenchymal Stem Cells
por: Patel, Shyam A., et al.
Publicado: (2008)

An in vitro method to select malignant cells from surgical biopsies of breast cancer patients
por: Corcoran, Kelly E., et al.
Publicado: (2005)

Emerging role of microRNAs in diagnosis and treatment of various diseases including ovarian cancer
por: Shah, Parag P, et al.
Publicado: (2009)

A Perspective of Immunotherapy for Breast Cancer: Lessons Learned and Forward Directions for All Cancers
por: Nahas, George R., et al.
Publicado: (2015)

Epigenetic Dysregulation at the Crossroad of Women’s Cancer
por: Kumar, Rakesh, et al.
Publicado: (2019)

Stem Cells as Potential Therapeutics and Targets for Infection by COVID19 – Special Issue on COVID19 in Stem Cell Reviews and Reports
por: Ratajczak, Mariusz Z., et al.
Publicado: (2021)

Cancer from the perspective of stem cells and misappropriated tissue regeneration mechanisms
por: Ratajczak, Mariusz Z., et al.
Publicado: (2018)

Isolation and characterization of mesenchymal stem cells in orthopaedics and the emergence of compact bone mesenchymal stem cells as a promising surgical adjunct
por: Anastasio, Albert, et al.
Publicado: (2020)

Correction: Cancer from the perspective of stem cells and misappropriated tissue regeneration mechanisms
por: Ratajczak, Mariusz Z., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8f95ta1b721fckpddmmr52n1pg