Effect of AMPK signal pathway on pathogenesis of abdominal aortic aneurysms

BACKGROUND AND AIMS: Determine the effect of AMPK activation and inhibition on the development of AAA (abdominal aortic aneurysm). METHODS: AAA was induced in ApoE(−/−) mice by Ang II (Angiotensin II)-infusion. AICAR (5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside) was used as AMPK activator an...

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Detalles Bibliográficos
Autores principales: Yang, Le, Shen, Lin, Gao, Peixian, Li, Gang, He, Yuxiang, Wang, Maohua, Zhou, Hua, Yuan, Hai, Jin, Xing, Wu, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696225/
https://www.ncbi.nlm.nih.gov/pubmed/29190959
http://dx.doi.org/10.18632/oncotarget.21608

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