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Blockade of Eosinophil-Induced Bronchial Epithelial-Mesenchymal Transition with a Geranyl Acetophenone in a Coculture Model
Epithelial-mesenchymal transition (EMT) is currently recognized as the main cellular event that contributes to airway remodeling. Eosinophils can induce EMT in airway epithelial cells via increased transforming growth factor (TGF)-β production. We assessed the effect of synthetic 2,4,6-trihydroxy-3-...
Autores principales: | Lee, Yu Z., Yap, Hui M., Shaari, Khozirah, Tham, Chau L., Sulaiman, Mohd R., Israf, Daud A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696322/ https://www.ncbi.nlm.nih.gov/pubmed/29201006 http://dx.doi.org/10.3389/fphar.2017.00837 |
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