Cargando…

Long-lived unipotent Blimp1-positive luminal stem cells drive mammary gland organogenesis throughout adult life

The hierarchical relationships between various stem and progenitor cell subpopulations driving mammary gland morphogenesis and homoeostasis are poorly understood. Conditional inactivation experiments previously demonstrated that expression of the zinc finger transcriptional repressor Blimp1/PRDM1 is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Elias, Salah, Morgan, Marc A., Bikoff, Elizabeth K., Robertson, Elizabeth J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696348/ https://www.ncbi.nlm.nih.gov/pubmed/29158490 http://dx.doi.org/10.1038/s41467-017-01971-w

Ejemplares similares

The transcriptional repressor Blimp1 is expressed in rare luminal progenitors and is essential for mammary gland development
por: Ahmed, Mohammed I., et al.
Publicado: (2016)

Blimp-1/PRDM1 is a critical regulator of Type III Interferon responses in mammary epithelial cells
por: Elias, Salah, et al.
Publicado: (2018)

The mammary stem cell conundrum: is it unipotent or multipotent?
por: Joshi, Purna A, et al.
Publicado: (2012)

Mapping the chromatin landscape and Blimp1 transcriptional targets that regulate trophoblast differentiation
por: Nelson, Andrew C., et al.
Publicado: (2017)

Blimp1/Prdm1 Functions in Opposition to Irf1 to Maintain Neonatal Tolerance during Postnatal Intestinal Maturation
por: Mould, Arne W., et al.
Publicado: (2015)

Unipotent algebraic groups
por: Kambayashi, Tatsuji, et al.
Publicado: (1974)

Renewal of the Holocrine Meibomian Glands by Label-Retaining, Unipotent Epithelial Progenitors
por: Parfitt, Geraint J., et al.
Publicado: (2016)

The transcriptional repressor Blimp1/PRDM1 regulates the maternal decidual response in mice
por: Goolam, Mubeen, et al.
Publicado: (2020)

Pancreatic Mesenchyme Regulates Epithelial Organogenesis throughout Development
por: Landsman, Limor, et al.
Publicado: (2011)

Id-1 is not expressed in the luminal epithelial cells of mammary glands
por: Uehara, Norihisa, et al.
Publicado: (2003)

Phenotypic and functional characterisation of the luminal cell hierarchy of the mammary gland
por: Shehata, Mona, et al.
Publicado: (2012)

Luminal Progenitors Restrict Their Lineage Potential during Mammary Gland Development
por: Rodilla, Veronica, et al.
Publicado: (2015)

Centres of centralizers of unipotent elements in simple algebraic groups
por: Lawther, R, et al.
Publicado: (2011)

The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells
por: Malhotra, Gautam K, et al.
Publicado: (2014)

VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland
por: Smith, Prestina, et al.
Publicado: (2019)

Intratumoral Heterogeneity of Expression of 16 miRNA in Luminal Cancer of the Mammary Gland
por: Veryaskina, Yuliya A., et al.
Publicado: (2020)

The Luminal Progenitor Compartment of the Normal Human Mammary Gland Constitutes a Unique Site of Telomere Dysfunction
por: Kannan, Nagarajan, et al.
Publicado: (2013)

On the unipotence of autoequivalences of toric complete intersection Calabi-Yau categories
por: Herbst, Manfred, et al.
Publicado: (2009)

Unipotent and nilpotent classes in simple algebraic groups and lie algebras
por: Liebeck, Martin W, et al.
Publicado: (2012)

Riemannian Means on Special Euclidean Group and Unipotent Matrices Group
por: Duan, Xiaomin, et al.
Publicado: (2013)

Kindlin-2 in myoepithelium controls luminal progenitor commitment to alveoli in mouse mammary gland
por: Wang, Zhenbin, et al.
Publicado: (2023)

Luminal-contact-inhibition of epithelial basal stem cell multipotency in prostate organogenesis and homeostasis
por: Horton, Corrigan, et al.
Publicado: (2019)

Bipotent Progenitors Do Not Require Androgen Receptor for Luminal Specification during Prostate Organogenesis
por: Shibata, Maho, et al.
Publicado: (2020)

Blimp1(+) cells generate functional mouse sebaceous gland organoids in vitro
por: Feldman, Alona, et al.
Publicado: (2019)

Humanization of the mouse mammary gland by replacement of the luminal layer with genetically-engineered preneoplastic human cells
por: Verbeke, Stephanie, et al.
Publicado: (2014)

Vitamin D receptor regulates autophagy in the normal mammary gland and in luminal breast cancer cells
por: Tavera-Mendoza, Luz E., et al.
Publicado: (2017)

p53 induces skin aging by depleting Blimp1(+) sebaceous gland cells
por: Kim, J, et al.
Publicado: (2014)

On stability and endoscopic transfer of unipotent orbital integrals on p-adic symplectic groups
por: Assem, Magdy
Publicado: (1998)

Minimal polynomials of unipotent elements in irreducible representations of the classical groups in odd characteristic
por: Suprunenko, ID
Publicado: (2009)

On the Galois cohomology of unipotent algebraic groups over local and global function fields
por: Nguyen, Q T, et al.
Publicado: (2004)

Inactivation of LATS1/2 drives luminal-basal plasticity to initiate basal-like mammary carcinomas
por: Kern, Joseph G., et al.
Publicado: (2022)

Two functionally distinct epithelial progenitors exist within the luminal cell compartment of the mouse mammary gland
por: Stingl, J, et al.
Publicado: (2008)

Luminal Epithelial Cells within the Mammary Gland Can Produce Basal Cells upon Oncogenic Stress
por: Hein, Sarah M., et al.
Publicado: (2015)

Erratum to: Humanization of the mouse mammary gland by replacement of the luminal layer with genetically engineered preneoplastic human cells
por: Verbeke, Stephanie, et al.
Publicado: (2015)

Luminal Rank loss decreases cell fitness leading to basal cell bipotency in parous mammary glands
por: Rocha, Ana Sofia, et al.
Publicado: (2023)

Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells
por: Liu, Ying, et al.
Publicado: (2016)

Unipotent, Atoh1(+) progenitors maintain the Merkel cell population in embryonic and adult mice
por: Wright, Margaret C., et al.
Publicado: (2015)

A label-retaining but unipotent cell population resides in biliary compartment of mammalian liver
por: Viil, Janeli, et al.
Publicado: (2017)

Serotoninergic and Circadian Systems: Driving Mammary Gland Development and Function
por: Suárez-Trujillo, Aridany, et al.
Publicado: (2016)

β-catenin is required in the neural crest and mesencephalon for pituitary gland organogenesis
por: Davis, Shannon W., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_k2ei7j9si6k1rjlaq3nmivii77