Application of the qSOFA score to predict mortality in patients with suspected infection in a resource-limited setting in Malawi

PURPOSE: To determine the predictive value of qSOFA (quick Sequential Organ Failure Assessment) in Malawian patients with suspected infection. METHODS: Prospective observational study in a tertiary referral hospital in Malawi. RESULTS: Predictive ability of qSOFA was reasonable [AUROC 0.73 (95% CI 0...

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Autores principales: Huson, Michaëla A. M., Katete, Chawezi, Chunda, Lilian, Ngoma, Jonathan, Wallrauch, Claudia, Heller, Tom, van der Poll, Tom, Grobusch, Martin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696439/
https://www.ncbi.nlm.nih.gov/pubmed/28786004
http://dx.doi.org/10.1007/s15010-017-1057-5
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author Huson, Michaëla A. M.
Katete, Chawezi
Chunda, Lilian
Ngoma, Jonathan
Wallrauch, Claudia
Heller, Tom
van der Poll, Tom
Grobusch, Martin P.
author_facet Huson, Michaëla A. M.
Katete, Chawezi
Chunda, Lilian
Ngoma, Jonathan
Wallrauch, Claudia
Heller, Tom
van der Poll, Tom
Grobusch, Martin P.
author_sort Huson, Michaëla A. M.
collection PubMed
description PURPOSE: To determine the predictive value of qSOFA (quick Sequential Organ Failure Assessment) in Malawian patients with suspected infection. METHODS: Prospective observational study in a tertiary referral hospital in Malawi. RESULTS: Predictive ability of qSOFA was reasonable [AUROC 0.73 (95% CI 0.68–0.78)], increasing to 0.77 (95% CI 0.72–0.82) when classifying all patients with altered mental status as high risk. Adding HIV status as a variable to the qSOFA score did not improve predictive value. CONCLUSION: qSOFA is a simple tool that can aid risk stratification in resource-limited settings. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s15010-017-1057-5) contains supplementary material, which is available to authorized users.
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spelling pubmed-56964392017-11-30 Application of the qSOFA score to predict mortality in patients with suspected infection in a resource-limited setting in Malawi Huson, Michaëla A. M. Katete, Chawezi Chunda, Lilian Ngoma, Jonathan Wallrauch, Claudia Heller, Tom van der Poll, Tom Grobusch, Martin P. Infection Brief Report PURPOSE: To determine the predictive value of qSOFA (quick Sequential Organ Failure Assessment) in Malawian patients with suspected infection. METHODS: Prospective observational study in a tertiary referral hospital in Malawi. RESULTS: Predictive ability of qSOFA was reasonable [AUROC 0.73 (95% CI 0.68–0.78)], increasing to 0.77 (95% CI 0.72–0.82) when classifying all patients with altered mental status as high risk. Adding HIV status as a variable to the qSOFA score did not improve predictive value. CONCLUSION: qSOFA is a simple tool that can aid risk stratification in resource-limited settings. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s15010-017-1057-5) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2017-08-07 2017 /pmc/articles/PMC5696439/ /pubmed/28786004 http://dx.doi.org/10.1007/s15010-017-1057-5 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Brief Report
Huson, Michaëla A. M.
Katete, Chawezi
Chunda, Lilian
Ngoma, Jonathan
Wallrauch, Claudia
Heller, Tom
van der Poll, Tom
Grobusch, Martin P.
Application of the qSOFA score to predict mortality in patients with suspected infection in a resource-limited setting in Malawi
title Application of the qSOFA score to predict mortality in patients with suspected infection in a resource-limited setting in Malawi
title_full Application of the qSOFA score to predict mortality in patients with suspected infection in a resource-limited setting in Malawi
title_fullStr Application of the qSOFA score to predict mortality in patients with suspected infection in a resource-limited setting in Malawi
title_full_unstemmed Application of the qSOFA score to predict mortality in patients with suspected infection in a resource-limited setting in Malawi
title_short Application of the qSOFA score to predict mortality in patients with suspected infection in a resource-limited setting in Malawi
title_sort application of the qsofa score to predict mortality in patients with suspected infection in a resource-limited setting in malawi
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696439/
https://www.ncbi.nlm.nih.gov/pubmed/28786004
http://dx.doi.org/10.1007/s15010-017-1057-5
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