Hypoxia inducible factor-1α mediates the profibrotic effect of albumin in renal tubular cells

Proteinuria is closely associated with the progression of chronic kidney diseases (CKD) by producing renal tubulointerstitial fibrosis. Over-activation of hypoxia inducible factor (HIF)-1α has been implicated in the progression of CKD. The present study tested the hypothesis that HIF-1α mediates alb...

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Detalles Bibliográficos
Autores principales: Hu, Junping, Wang, Weili, Zhang, Fan, Li, Pin-Lan, Boini, Krishna M., Yi, Fan, Li, Ningjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696482/
https://www.ncbi.nlm.nih.gov/pubmed/29158549
http://dx.doi.org/10.1038/s41598-017-15972-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696482/
https://www.ncbi.nlm.nih.gov/pubmed/29158549
http://dx.doi.org/10.1038/s41598-017-15972-8

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