A phase I, randomized, single-dose study evaluating the pharmacokinetic equivalence of biosimilar ABP 215 and bevacizumab in healthy adult men

PURPOSE: This study compared the pharmacokinetic (PK) profiles of the proposed biosimilar ABP 215 with bevacizumab in healthy males. METHODS: In this randomized, single-blind, single-dose, three-arm, parallel-group study, healthy subjects were randomized to receive ABP 215 (n = 68), bevacizumab (US)...

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Detalles Bibliográficos
Autores principales: Markus, Richard, Chow, Vincent, Pan, Zhiying, Hanes, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696486/
https://www.ncbi.nlm.nih.gov/pubmed/28864922
http://dx.doi.org/10.1007/s00280-017-3416-4

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