Optogenetic silencing of nociceptive primary afferents reduces evoked and ongoing bladder pain

Patients with interstitial cystitis/bladder pain syndrome (IC/BPS) suffer from chronic pain that severely affects quality of life. Although the underlying pathophysiology is not well understood, inhibition of bladder sensory afferents temporarily relieves pain. Here, we explored the possibility that...

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Detalles Bibliográficos
Autores principales: Samineni, Vijay K., Mickle, Aaron D., Yoon, Jangyeol, Grajales-Reyes, Jose G., Pullen, Melanie Y., Crawford, Kaitlyn E., Noh, Kyung Nim, Gereau, Graydon B., Vogt, Sherri K., Lai, H. Henry, Rogers, John A., Gereau, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696510/
https://www.ncbi.nlm.nih.gov/pubmed/29158567
http://dx.doi.org/10.1038/s41598-017-16129-3

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